Medication info
JBKHC Tablet 5/20/12.5 mg

JBKHC Tablet 5/20/12.5 mg

Prescription medicationTablet경구
Ingredient · strength
Olmesartan Medoxomil›20mg / 1 tabletAmlodipine Besylate›6.944mg / 1 tabletHydrochlorothiazide›12.5mg / 1 tablet
Manufacturer / importer
(주)비보존제약
Appearance
White and orange round film-coated tablets
Packaging
30 tablets (10 tablets/Alu-Alu × 3)
Approval status
Active

MFDS item code 201805389 · Approved 2018.12.31 · Insurance code 658204170

Summary

Main use
Improvement of blood pressure control in essential hypertension
Who takes it
Adults · Children
Adult dose
This medication is taken once daily, with water, regardless of meals. It is recommended to take it at the same time each day (e.g. in the morning). The recommended dosing is as follows: - 5/20/12.5 mg: Prescribed for patients whose blood pressure is not adequately controlled with the Amlodipine/Olmesartan Medoxomil 5/20 mg combination therapy. - 5/40/12.5 mg: Prescribed for patients with Amlodipine/Olmesartan Medoxomil 5/40 mg combination therapy or those not adequately controlled with this medication 5/20/12.5 mg.
Child dose
The safety and efficacy for pediatric patients under 18 years of age have not been established, so the use of this medication is not recommended.

Ingredients

Manufacturer
(주)비보존제약

Efficacy & effects

Improvement of blood pressure control in essential hypertension

  • Essential hypertension
View approved original text

It is important to note that for patients with essential hypertension whose blood pressure is not sufficiently controlled even with combination therapy of Amlodipine and Olmesartan Medoxomil, additional treatment may be necessary. Proper blood pressure control is extremely important for reducing the burden on the heart and blood vessels and lowering the risk of complications. In such cases, the physician may recommend medication adjustment, dose changes, or alternative therapies. It is advisable for patients to engage in lifestyle modifications along with regular blood pressure measurements. Effective blood pressure management helps in the prevention of cardiovascular diseases.

How to take

Adult dose

This medication is taken once daily, with water, regardless of meals. It is recommended to take it at the same time each day (e.g. in the morning). The recommended dosing is as follows: - 5/20/12.5 mg: Prescribed for patients whose blood pressure is not adequately controlled with the Amlodipine/Olmesartan Medoxomil 5/20 mg combination therapy. - 5/40/12.5 mg: Prescribed for patients with Amlodipine/Olmesartan Medoxomil 5/40 mg combination therapy or those not adequately controlled with this medication 5/20/12.5 mg.

Child dose

The safety and efficacy for pediatric patients under 18 years of age have not been established, so the use of this medication is not recommended.

Precautions

This medication can cause serious harm to the fetus and newborn during the second and third trimesters of pregnancy, so it should be discontinued immediately if pregnancy is confirmed. Patients with allergies or hypersensitivity to any components of this medication or related drugs should not take it. Pregnant or breastfeeding women, patients with severe hypotension, or those with serious heart or kidney diseases should also not use this medication. Patients with decreased blood volume or electrolyte imbalances may experience hypotension at the initial stages of treatment with this medication, thus careful monitoring is required. Patients with impaired kidney function or those who have received kidney transplants should have frequent blood tests to monitor kidney function and electrolyte status during the use of this medication. Patients with poor liver function or ongoing liver disease may experience serious problems such as hepatic coma, therefore this medication should be administered with caution. This medication lowers blood pressure and may cause dizziness or orthostatic hypotension, so caution is warranted when driving or operating dangerous machinery. The component Hydrochlorothiazide can cause photosensitivity reactions, so the skin should be protected from sun exposure, and if adverse reactions occur, the medication should be discontinued. This medication can affect potassium levels in the blood, so potassium supplements or potassium-sparing diuretics should be used with caution, monitoring blood potassium levels carefully. When used in combination with other antihypertensive agents or certain medications, interactions may increase the risk of side effects, so it is important to consult with a doctor or pharmacist before use. Elderly patients might have decreased kidney and liver function, so it is advised to start at a low dose and adjust carefully. In the case of overdose, severe hypotension, palpitations, electrolyte imbalances may occur, and immediate medical attention is required for proper treatment. The safety and efficacy of this medication have not been established in children, so its use is not recommended. Store this medication in a place out of reach of children and avoid humidity, heat, and direct sunlight.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, cough with fever accompanied respiratory abnormalities, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, vision abnormalities, paralysis, urine changes

Mild side effects

  • Peripheral edema
  • headache
  • dizziness
  • upper respiratory infection
  • nasopharyngitis
  • urinary tract infection
  • sialadenitis
  • leukopenia
  • thrombocytopenia
  • bone marrow suppression
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  • neutropenia/agranulocytosis
  • hemolytic anemia
  • aplastic anemia
  • drug hypersensitivity
  • hyperkalemia
  • hypokalemia
  • loss of appetite
  • diabetes
  • hypercalcemia
  • hyperglycemia
  • hypomagnesemia
  • hyponatremia
  • hypochloremia
  • hypertriglyceridemia
  • hypercholesterolemia
  • hyperuricemia
  • hypochloremic metabolic alkalosis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is recommended to keep the storage temperature between 1 and 30 degrees Celsius. This will help maintain the effectiveness and safety of the drug over time.

Appearance and packaging

Appearance

White and orange round film-coated tablets

Package unit

30 tablets (10 tablets/Alu-Alu × 3)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.