Oroten HCT Tablet 5/40/12.5 mg

Adult dosage

This medication is taken once daily, with one tablet taken with water regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning). The recommended dosing is as follows: - 5/20/12.5 mg: administered to patients for whom blood pressure is not adequately controlled with the combination therapy of amlodipine/olmesartan medoxomil 5/20 mg. - 5/40/12.5 mg: administered to patients for whom blood pressure is not adequately controlled with the combination therapy of amlodipine/olmesartan medoxomil 5/40 mg.

Children's dosage

The safety and efficacy for pediatric patients under 18 years have not been established, so administration of this medication is not recommended.

This medication can cause serious harm to the fetus and newborn during the second and third trimesters of pregnancy, so it must not be taken during pregnancy. If pregnancy is confirmed, discontinue use immediately. Patients who have had allergies or hypersensitivity reactions to this medication or any of its components, women who are pregnant or breastfeeding, patients with severe hypotension or serious heart conditions, patients with severe kidney or liver diseases, and patients with electrolyte imbalances should not take this medication. Patients with reduced blood volume or electrolyte imbalances may experience hypotension; thus, the condition should be confirmed before administration, and continuous monitoring is required after treatment initiation. If hypotensive symptoms occur, rest immediately by lying down and administer fluids if necessary. This medication may affect kidney function, so patients with decreased kidney function should regularly check their kidney function and electrolyte status through blood tests. Particular caution is required when administering this medication to patients with liver disease or severe cirrhosis, certain heart valve diseases, systemic lupus erythematosus patients, and elderly individuals. This medication can cause photosensitive reactions on the skin, so avoid excessive exposure to sunlight or ultraviolet rays and consult a doctor immediately if any skin abnormalities arise. Dizziness or drowsiness may occur while taking this medication, so caution should be exercised when driving or engaging in hazardous activities. Drug interactions may occur when taken with other medications, especially lithium, diuretics, nonsteroidal anti-inflammatory drugs (NSAIDs), and other antihypertensive medications; patients should consult with their doctor or pharmacist if taking these drugs. In cases of overdose, severe hypotension or heart problems may occur, requiring immediate emergency treatment, so caution is necessary to avoid exceeding the prescribed dosage. Safety and efficacy have not been established for children, and use is not recommended; elderly patients should start at a low dose considering reduced kidney and liver function. Store this medication in a location out of reach of children, and keep it away from moisture, heat, and direct sunlight.

Serious side effects

• Hives, angioedema, Quincke's edema, anaphylactic reactions, severe allergic reactions.
• Severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes.
• Stevens-Johnson syndrome, toxic epidermal necrolysis, severe skin adverse reactions.
• Shortness of breath, respiratory distress syndrome, pulmonary edema, acute respiratory distress syndrome (ARDS).
• Yellowing of the skin or eyes (jaundice), acute hepatitis, jaundice (cholestatic jaundice).
• Acute.

Mild side effects

• Peripheral edema
• headache
• dizziness
• upper respiratory infection
• rhinitis
• urinary tract infection
• sialadenitis
• leukopenia
• thrombocytopenia
• bone marrow suppression

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is recommended to maintain storage temperatures between 1 and 30 degrees Celsius. Proper storage will help maintain the medication's efficacy.

Appearance

Pale yellow round film-coated tablet

Package unit

28 tablets (14 tablets/PTP × 2) / carton