Sebiduo HCT Tablet 5/20/12.5 Milligrams

Adult dose

This medication should be taken once daily as one tablet, with or without food. It is recommended to take it at the same time each day (e.g., in the morning). The maximum dosage is 10/40/25mg of amlodipine/olmesartan medoxomil/hydrochlorothiazide. The recommended dosing regimen is as follows: - 5/20/12.5mg: for patients whose blood pressure is not adequately controlled with amlodipine/olmesartan medoxomil 5/20mg combination therapy.

Child dose

The safety and efficacy of this medication in pediatric patients under 18 years of age have not been established; therefore, its use is not recommended.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy. Therefore, it should be stopped immediately upon confirmation of pregnancy. Patients with allergies to this drug or its components, or those with certain heart, kidney, or liver diseases, should not take this medication. It may be dangerous to use this drug in cases of severely low blood pressure, acute heart failure, or severe kidney or liver dysfunction. Patients with decreased blood volume or electrolyte imbalances should be closely monitored for hypotension when starting this medication. This drug may affect kidney function, so patients with kidney problems or severe heart failure should regularly have blood tests to check kidney function and electrolyte levels. Patients with liver disease, especially those with progressive liver cirrhosis, require careful monitoring when taking this medication. Patients with eye diseases, particularly acute angle-closure glaucoma, should be cautious as some components of this medication may exacerbate symptoms. This drug may interact with certain medications, increasing the risk of side effects when taken with lithium, some analgesics, or other antihypertensives; therefore, consultation with healthcare professionals is essential. Dizziness, headaches, edema, gastrointestinal disturbances, and other side effects may occur during treatment, and any unusual symptoms should be reported immediately. This medication is also available for elderly patients; however, as there may be decreased kidney or liver function, it is recommended to start at lower doses and monitor closely. Overdose may lead to severe hypotension or arrhythmias; therefore, adherence to dosage is vital, and if symptoms occur, immediate medical attention is necessary. This medication should be stored in a tightly sealed container away from direct sunlight and moisture, out of reach of children, and it is advised not to change the container arbitrarily. If breastfeeding, it is recommended to discontinue either breastfeeding or this medication as the components may pass into breast milk. The safety and efficacy of this medication have not been established in children under 18 years of age, so its use is not recommended.

Serious side effects

• Hives, severe swelling (edema), anaphylactic reactions, angioedema, Quincke's edema, severe allergic reactions
• Severe rash with high fever, blisters, skin peeling, oral/ocular mucosal pain, Stevens-Johnson syndrome, toxic epidermal necrolysis, severe skin adverse reactions
• Shortness of breath or difficulty breathing, asthma attacks, respiratory anomalies accompanied by cough + fever, dyspnea, pulmonary edema, acute interstitial pneumonia, respiratory distress syndrome, acute respiratory distress

Mild side effects

• Peripheral edema
• headaches
• dizziness
• upper respiratory infections
• nasopharyngitis
• urinary tract infections
• salivary gland inflammation
• leukopenia
• thrombocytopenia
• bone marrow suppression

This medication should be stored in a tightly sealed container to prevent exposure to air and light, at temperatures between 1 degree and 30 degrees Celsius. Proper storage will maintain the effectiveness of the medication and ensure safe use.

Appearance

White and orange round film-coated tablet

Package unit

28 tablets (14 tablets/PTPX2)