Olmesartan Medoxomil/Amlodipine Besylate/Hydrochlorothiazide Tablet 5/40/12.5 mg

Adult dose

This medication should be taken once daily, with one tablet at any time, regardless of meals. It is recommended to take it at the same time each day (e.g., in the morning). The maximum dosage is Amlodipine/Olmesartan Medoxomil/Hydrochlorothiazide of 10/40/25 mg. Adjust doses with intervals of more than 2 weeks considering blood pressure responses. Recommended dosages include 5/20/12.5 mg, 5/40/12.5 mg, 5/40/25 mg.

Child dose

Safety and efficacy in pediatric patients under 18 years have not been established, and the use of this medication is not recommended.

This medication should not be used during the second and third trimesters of pregnancy. Taking it during pregnancy may cause serious harm to the fetus or newborn, so usage must be stopped immediately upon confirmation of pregnancy. Patients with a history of allergy or hypersensitivity to any components of this medication or similar drugs, pregnant or nursing women, patients with severe hypotension or heart valve diseases, and those with unstable heart failure following acute myocardial infarction should not be administered this drug. Patients with severely impaired kidney or liver function, hyponatremia, hypokalemia, hypercalcemia, gout, and certain other conditions should use this medication carefully and frequently monitor blood pressure, kidney function, and electrolyte levels before and during treatment. Since this drug has a blood pressure-lowering effect, it may cause low blood pressure leading to dizziness or orthostatic hypotension. If these symptoms occur, notify healthcare professionals immediately, and be cautious when driving or operating hazardous machinery. This drug can interact with other antihypertensive medications, diuretics, lithium, non-steroidal anti-inflammatory drugs (NSAIDs), so inform healthcare professionals of any other medications being taken. During treatment, regular blood tests to monitor kidney function, electrolytes, blood glucose, and cholesterol levels are necessary, and consult a doctor if any unusual symptoms occur. This medication is not recommended for nursing women, and if necessary, breastfeeding should be discontinued or alternative treatment options considered. In cases of overdose, severe hypotension, palpitations, bradycardia, and electrolyte imbalances may occur, requiring immediate medical attention at a hospital. This medication should be stored in a tightly sealed container, away from direct sunlight and moisture, out of reach of children, and should not be transferred to different containers.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue throughout the body, sudden and severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, very low urine output.

Mild side effects

• Peripheral edema
• headache
• dizziness
• upper respiratory infection
• nasopharyngitis
• urinary tract infection
• sialadenitis
• leukopenia
• thrombocytopenia
• bone marrow suppression

Store this medication in a tightly sealed container to prevent air or moisture ingress, at a temperature between 1 to 30 degrees Celsius room temperature. This storage method will help maintain the drug's efficacy for a longer period.

Appearance

Light yellow round film-coated tablet

Package unit

28 tablets (14 tablets/PTP X 2)/carton