Olmephos H Tablet 5/20/12.5 mg (Amlodipine Besylate, Olmesartan Medoxomil, Hydrochlorothiazide)

Adult dose

This medication should be taken once a day at a dose of one tablet, with water, regardless of meals. It is recommended to take it at the same time daily (e.g., in the morning). The maximum dosage is Amlodipine/Olmesartan Medoxomil/Hydrochlorothiazide at 10/40/25 mg. Doses may be adjusted based on blood pressure control at intervals of at least 2 weeks. Recommended dosing steps are as follows: - 5/20/12.5 mg - 5/40/12.

Child dose

Safety and efficacy in pediatric patients under 18 years of age have not been established; therefore, the use of this medication is not recommended.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. Patients with hypersensitivity to any component of this drug, those with certain cardiac, renal, or liver diseases, as well as pregnant or breastfeeding women, and patients with severe hypotension should not take this drug. Patients with low blood volume or low sodium may experience hypotension at the start of treatment with this drug; therefore, sufficient status checks before taking this medication and careful observation afterwards are necessary. This medication can affect kidney function, thus patients with impaired renal function should frequently check their kidney function through blood tests. Patients with poor liver function or liver disease should be cautious, as hepatic coma may occur with this drug, and it is not recommended for patients with severe hepatic impairment. As this medication lowers blood pressure, it may cause orthostatic hypotension or dizziness, so caution is advised while driving or operating hazardous machinery. Patients taking this medication may experience electrolyte imbalances, so it is important to regularly check electrolyte levels through blood tests. The Hydrochlorothiazide component can cause photosensitivity reactions; therefore, exposure to sunlight or ultraviolet light should be avoided, and if any unusual reactions occur, the medication should be discontinued immediately. This medication may interact with other antihypertensive medications or certain drugs, so if you are taking other medications, be sure to inform your doctor or pharmacist. Overdose can lead to severe hypotension or arrhythmia, and if symptoms occur, immediate medical attention should be sought. This medication is not recommended for use in children, and elderly patients should start with a lower dose considering possible renal and liver function decline. During breastfeeding, the ingredients of this medication may pass into breast milk, so breastfeeding women should discontinue breastfeeding or consult a physician when taking this drug. This medication should be stored in a moisture- and heat-free environment and kept out of reach of children. Do not transfer to other containers.

Serious side effects

Urticaria, angioedema, Quincke's edema, severe swelling (edema), tightness in the chest, difficulty breathing, anaphylactic reaction, severe rash with fever, blisters, skin shedding, pain in oral/ocular mucosa, Stevens-Johnson syndrome, paralytic ileus, acute renal failure, renal failure, jaundice, hepatitis, acute interstitial pneumonia, jaundice (cholestatic jaundice), acute cholecystitis, acute angle-closure glaucoma, acute respiratory distress syndrome (ARDS)

Mild side effects

• Peripheral edema
• headache
• dizziness
• upper respiratory tract infections
• rhinitis
• urinary tract infections
• sialadenitis
• leukopenia
• thrombocytopenia
• bone marrow suppression

This medication is sensitive to air and moisture and must be stored in a tightly sealed container. The storage temperature should maintain between 1 degree and 30 degrees Celsius.

Appearance

White-orange round film-coated tablets

Package unit

28 tablets (14 tablets/PTP x 2) / carton