Medication info
Okovast Tablet 20 mg (Atorvastatin Calcium Trihydrate)

Okovast Tablet 20 mg (Atorvastatin Calcium Trihydrate)

Prescription medicationTablet
Ingredient · strength
Atorvastatin Calcium Hydrate›21.7mg / 1 tablet
Manufacturer / importer
(주)오스코리아제약
Appearance
White round film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 201805137 · Approved 2018.12.18 · Insurance code 629701510

Summary

Main use
Reduction of the risk of myocardial infarction and stroke, and improvement of hyperlipidemia
Who uses it
Adults · Children
Adult dosage
Atorvastatin can be taken at any time during the day, regardless of food. The recommended initial dose for hyperlipidemia is 10 mg once daily, and if a greater reduction in LDL cholesterol is needed, it can be started at 20 mg or 40 mg once daily. Dosing ranges from 10 mg to 80 mg once daily. After initiating therapy and adjusting the dose, lipid levels should be analyzed within 2 to 4 weeks to adjust the dosage accordingly.
Children's dosage
The recommended initial dose for pediatric patients (ages 10-17) with heterozygous familial hypercholesterolemia is 10 mg once daily, with a maximum recommended dose of 20 mg per day. The dosage should be adjusted at intervals of at least 4 weeks.

Ingredients

Manufacturer
(주)오스코리아제약

Efficacy & effects

Reduction of the risk of myocardial infarction and stroke, and improvement of hyperlipidemia

  • Myocardial infarction
  • stroke
  • vascular interventions
  • chronic stable angina
  • retinopathy
  • albuminuria
  • heart failure
  • angina
  • hypercholesterolemia
  • dyslipidemia
  • abnormal beta-lipoproteinemia
  • elevated serum triglycerides
View approved original text

This medication is used to effectively reduce the risk of cardiovascular diseases. In particular, it decreases the risk of myocardial infarction and stroke, as well as reduces the need for vascular interventions and the risk of chronic stable angina. It is also beneficial for adults with multiple risk factors such as hypertension, smoking, and family history, as well as patients with type 2 diabetes. Additionally, it contributes to reducing the risk of hospitalization due to heart failure and alleviating angina symptoms. For patients with hyperlipidemia, it helps lower total cholesterol, LDL cholesterol, and triglyceride levels while increasing HDL cholesterol to maintain a healthy lipid profile. Furthermore, pediatric patients aged 10 to 17 with hypercholesterolemia can improve their blood lipid levels with this medication. Therefore, this drug is very useful in promoting cardiovascular health and preventing related diseases.

Dosage and Administration

Adult dosage

Atorvastatin can be taken at any time during the day, regardless of food. The recommended initial dose for hyperlipidemia is 10 mg once daily, and if a greater reduction in LDL cholesterol is needed, it can be started at 20 mg or 40 mg once daily. Dosing ranges from 10 mg to 80 mg once daily. After initiating therapy and adjusting the dose, lipid levels should be analyzed within 2 to 4 weeks to adjust the dosage accordingly.

Children's dosage

The recommended initial dose for pediatric patients (ages 10-17) with heterozygous familial hypercholesterolemia is 10 mg once daily, with a maximum recommended dose of 20 mg per day. The dosage should be adjusted at intervals of at least 4 weeks.

Precautions

This medication may pose a risk of muscle problems, so if symptoms such as muscle pain, muscle weakness, or severe fatigue occur, you should inform your doctor immediately. In particular, if there is a significant elevation in creatine kinase levels from blood tests, the use of this drug should be discontinued. This medication may affect liver function, so it should not be used in individuals with liver disease or elevated liver enzyme levels. Pregnant women or women who may become pregnant, as well as nursing mothers, should not take this drug. Additionally, children under 10 years old or patients with muscle disorders should not use this medication. Patients with a history of alcoholism or liver disease should use this drug cautiously and undergo regular liver function tests. This medication can interact with other drugs, so care should be taken when used in conjunction with certain antibiotics, antifungals, HIV medications, some heart medications, and grapefruit juice. If symptoms such as muscle pain, muscle weakness, fever, or fatigue appear during treatment, you should consult your doctor immediately. This drug may cause side effects such as liver dysfunction, allergic reactions, skin rashes, indigestion, headaches, and insomnia, so if symptoms persist or worsen, notify your healthcare provider. Elderly patients or those with kidney impairment are at a higher risk for muscle problems, so they should use this medication with extra caution. While taking this drug, it is important to regularly test blood and liver function to check for abnormalities. In the case of overdose, there is no specific antidote, and treatment should be based on symptoms, and it should be stored safely out of reach of children.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rashes accompanied by high fever, blisters, skin peeling, pain in mucous membranes of the mouth/eyes, severe skin reactions, difficulty breathing or shortness of breath, asthma attacks, respiratory issues accompanied by cough and fever, jaundice (yellowing of the skin or eyes), extreme lethargy, liver issues (jaundice), sudden and

Mild side effects

  • Weakness
  • fatigue
  • chest pain
  • peripheral edema
  • malaise
  • fever
  • rhinitis
  • hyperglycemia
  • hypoglycemia
  • weight gain
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  • loss of appetite
  • constipation
  • bloating
  • indigestion
  • nausea
  • diarrhea
  • abdominal pain
  • vomiting
  • belching
  • pancreatitis
  • throat and laryngeal pain
  • nosebleeds
  • insomnia
  • nightmares
  • headaches
  • dizziness
  • paresthesia
  • sensory loss
  • taste disturbances
  • memory loss
  • peripheral neuropathy
  • myalgia
  • arthralgia
  • limb pain
  • musculoskeletal pain
  • muscle cramps
  • joints

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture. The recommended storage temperature is at room temperature between 1°C and 30°C. This helps maintain the drug's effectiveness for a longer period.

Appearance and packaging

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.