Zantac Tablet (Ranitidine Hydrochloride)

Adult dose

Adults should take 150 mg of ranitidine orally twice a day, in the morning and at bedtime. - Gastric/Duodenal Ulcer: 150 mg once, twice a day or 300 mg once a day (at bedtime); for duodenal ulcer patients, 300 mg can be administered twice daily. - Maintenance therapy for recurrent ulcers: 150 mg once daily at bedtime. - Gastroesophageal reflux disease

Child dose

For children, clinical studies are not established; however, for those aged 8 to 18, 150 mg (2 mg per kg body weight) can be administered once, up to twice a day.

This medication should not be used in patients who have had an allergic reaction to this drug or its components. Avoid administration in patients with a history of acute porphyria, as this drug may precipitate seizures. Patients with impaired kidney function may have increased blood concentration due to renal excretion, requiring dose adjustments. Patients with liver dysfunction should also use this medication with caution. Patients with a history of drug allergy or elderly patients should administer this drug carefully. When combined with non-steroidal anti-inflammatory drugs, especially in the elderly or those with a history of peptic ulcers, regular monitoring of the condition is necessary. This medication may mask symptoms of gastric cancer, so it should be confirmed that it is not cancer if symptoms of gastric ulcer or dyspepsia arise or change in middle-aged patients or older. Patients with gastric and duodenal ulcers with Helicobacter pylori infection should undergo bacterial eradication therapy. Rarely, this medication can cause severe allergic reactions or anaphylactic shock, so if any unusual symptoms occur during administration, treatment should be discontinued immediately. If skin rashes, hives, or bronchospasm occur, use should be discontinued. Various side effects, including blood-related symptoms, liver dysfunction, cardiac arrhythmias, gastrointestinal symptoms, and neurological symptoms may rarely occur, so any unusual symptoms should be reported immediately. Patients with poor kidney function should particularly be cautious of symptoms such as mental confusion or seizures. This medication should be used at the minimum dose while confirming the therapeutic effect, and if ineffective, other treatments should be considered. Elderly patients and those with chronic lung disease, diabetes, or weakened immune systems may have an increased risk of pneumonia, which should be monitored carefully. Avoid driving or operating dangerous machinery if dizziness or drowsiness occurs. This medication may interact with other drugs, so inform your doctor or pharmacist about any concurrent medications. In particular, cautiously observe for bleeding risks when used with warfarin. Women who are pregnant or may become pregnant, as well as nursing mothers, should carefully consider the risks and benefits if this medication is necessary. Safety in pediatric patients has not been sufficiently established, so caution is needed when using. Elderly patients may require dose adjustments due to increased drug concentration from decreased kidney function. Overdose is rarely accompanied by specific toxic symptoms, but gastric lavage or symptomatic treatment should be provided if necessary. Keep out of reach of children and do not transfer to other containers.

Serious side effects

• Hives
• angioedema
• shock (anaphylactic shock)
• bronchospasm
• hypotension
• chest pain
• thrombocytopenia
• leukopenia
• bone marrow suppression
• aplastic anemia

Mild side effects

• Rash
• fever
• elevated serum creatinine levels
• bradycardia
• atrioventricular block
• tachycardia
• constipation
• nausea
• vomiting
• abdominal fullness

This medication should be stored in a tightly sealed container that protects from light, at a temperature between 1 to 30 degrees Celsius. Storing it this way will help safely maintain the effectiveness of the medication.

Appearance

Pale yellow to yellow round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle