Twin Down Tablet 40/5 mg

Adult dose

The recommended dose of this medication is 1 tablet once daily, to be taken with water, regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). It can be administered in doses of 40/5 mg, 80/5 mg, or 40/10 mg, depending on the blood pressure control situation. Patients with renal impairment should start with a lower dose in more severe cases and gradually increase the dose, while patients with liver impairment should not exceed a daily dose of 40 mg.

Child dose

Safety and efficacy have not been established for pediatric patients under the age of 18, so its use is not recommended.

This medication can cause serious harm to the fetus during pregnancy, especially in the second and third trimesters. Therefore, it must not be used by women who are pregnant or may become pregnant. If pregnancy is confirmed, use should be discontinued immediately, and if necessary, it should be replaced with other safe medications. This medication is contraindicated in patients with certain conditions. For example, individuals allergic to any component of this medication, pregnant women, breastfeeding women, patients with biliary obstruction, severe liver impairment, severe heart diseases, severe hypotension, patients in shock, unstable heart failure after acute myocardial infarction, and certain kidney diseases cannot use this medication. Moreover, patients with primary aldosteronism, certain heart valve diseases, weakened liver function, gastrointestinal diseases, renal artery hypertension, patients undergoing dialysis, and the elderly must use this medication with caution, requiring dose adjustments or close monitoring by a physician. This medication can commonly cause side effects such as dizziness and peripheral edema, while rare side effects may include fainting or serious heart issues. If side effects are suspected, immediate consultation with a healthcare professional is necessary. Drug interactions should also be monitored carefully. Caution is required when taken with other antihypertensive medications, certain diuretics, potassium supplements, lithium, digoxin, warfarin, grapefruit juice, etc., and regular monitoring of kidney function and serum potassium levels is critical. It is safest for pregnant or breastfeeding women not to use this medication, and it should also be avoided during breastfeeding. The safety and efficacy of this medication have not been established for pediatric patients under 18 years of age, so its use is not recommended. In elderly patients, doses should be adjusted gradually and used with caution, as overdose may lead to hypotension, heart problems, or kidney damage, requiring immediate medical attention. This medication should be kept out of reach of children and should be opened just before use as it is sensitive to moisture.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rashes with fever, blisters, skin peeling, pain in mouth/eyes mucous membranes, difficulty breathing or shortness of breath, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), severe fatigue, sudden and very severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, decreased urine output.

Mild side effects

• Dizziness
• peripheral edema
• upper respiratory infection
• urinary tract infection
• anemia
• hyperkalemia
• hypoglycemia
• hyponatremia
• hyperglycemia
• depression

This medication should be stored in a special container to avoid exposure to light and air. It is recommended to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

It is a biconvex oval double tablet, white and light gray.

Package unit

30 tablets (10 tablets/PTP x 3)