Pabiserabeprazole 20 mg (Rabeprazole Sodium)

Adult dose

For gastric ulcers and duodenal ulcers: Typically, 10 mg is taken orally once daily, and depending on symptoms, it may be increased to 20 mg once daily. The duration of treatment is 8 weeks for gastric ulcers and 6 weeks for duodenal ulcers. For erosive or ulcerative gastroesophageal reflux disease: 10 mg or 20 mg is administered once daily for 4 to 8 weeks, and if not relieved after 8 weeks, an additional 8 weeks of 10 mg or 20 mg taken twice daily may be given.

Child dose

Safety for children has not been established.

This medication should be avoided by individuals allergic to certain components or benzimidazoles. Additionally, those with allergies to penicillin-type or macrolide antibiotics used for eradicating Helicobacter pylori should also avoid this medication. It is not safe for women during pregnancy or breastfeeding. Patients with compromised liver function or the elderly should use this medication cautiously, and those with a history of allergies should also take care. If allergic symptoms like rash, hives, or itching occur during this treatment, it is important to stop taking this medication immediately and consult a physician. Regular blood tests and liver function tests should be performed, and if any abnormal signs are found, discontinuation of the medication and appropriate treatment should be initiated. Various side effects can occur in multiple systems including the heart, gastrointestinal tract, nervous system, respiratory system, and skin, so it is crucial to report any severe or unusual symptoms to healthcare providers. Long-term use may increase the risk of fractures due to osteoporosis, so caution is advised. Electrolyte imbalances such as hypomagnesemia may occur, and routine monitoring of magnesium levels is recommended for long-term users. This medication strongly inhibits gastric acid secretion, which could slightly increase the risk of bacterial infections in the stomach; if diarrhea persists, it should be discussed with a healthcare provider. There is a risk of accidents due to drowsiness while driving or operating machinery, so caution is warranted. This medication may interact with other drugs, so especially when taken with warfarin, antibiotics, or antivirals, consultation with a physician or pharmacist is necessary. It is not recommended for use during pregnancy or breastfeeding, and pregnant or breastfeeding women should definitely consult with experts. The elderly may be more susceptible to side effects due to decreased liver function, so if any abnormal symptoms occur, temporary discontinuation and consultation with a physician is advised. The safety of this medication for children has not been established, so it is advisable not to use it in children. This medication should be swallowed whole and not chewed or crushed, and it should be stored out of reach of children. Long-term use may lead to impaired absorption of vitamin B12, so periodic testing may be necessary. In cases of overdose, there is no specific antidote, so appropriate treatment and supportive care should be administered based on the symptoms.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, skin peeling, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, jaundice (yellowing of the skin or eyes), severe lethargy, sudden and very severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, decreased urine output.

Mild side effects

• Rash
• itching
• decreased red blood cells
• decreased white blood cells
• increased white blood cells
• increased eosinophils
• increased neutrophils
• decreased lymphocytes
• anemia
• petechiae

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius. Storing it this way will help preserve the effectiveness of the medication for a long time.

Appearance

Light yellow round enteric-coated tablet

Package unit

28 tablets/box [14 tablets/AluAlu*2]