Lorofen 60 mg (Loxoprofen Sodium Hydrate)

Adult dose

1. For indications 1 and 2: ○ Adults: Loxoprofen sodium (anhydrous) 60 mg orally three times daily. In single-dose therapy, 60-120 mg can be administered orally. 2. For indication 3: ○ Adults: Loxoprofen sodium (anhydrous) 60 mg is administered orally. Generally, it can be taken twice a day, with a maximum of 180 mg per day. It is preferred to avoid taking on an empty stomach.

This medication may pose a risk of gastric bleeding if taken by individuals who regularly consume alcohol in excess of three glasses a day, thus consultation with a doctor or pharmacist is necessary. This medication can affect the cardiovascular system, so individuals at risk of heart disease or stroke should be particularly cautious and report any cardiac symptoms to healthcare professionals immediately. Gastric bleeding or ulcers may occur, so senior patients or those with a history of gastrointestinal disorders should closely monitor their gastrointestinal status during treatment. Patients with peptic ulcers, severe blood disorders, serious liver or kidney disease, heart failure, allergies to aspirin or nonsteroidal anti-inflammatory drugs, pregnant women in the late stages of pregnancy, and breastfeeding mothers should not take this medication. Individuals with a history of peptic ulcers, blood disorders, or liver or kidney issues should follow healthcare professional guidance when taking this medication. This drug may cause hypersensitivity reactions such as skin rashes, itching, and urticaria, and such symptoms necessitate immediate cessation of the medication and consultation with a doctor. Gastrointestinal symptoms such as abdominal pain, vomiting, diarrhea, and dyspepsia may occur, and in severe cases, it may lead to bleeding or perforation, warranting immediate medical attention if symptoms are severe. Neurological symptoms such as dizziness, drowsiness, and headaches may also occur, necessitating caution while driving or operating machinery. Serious side effects such as abnormal liver function, decreased kidney function, and blood disorders may occur, thus regular blood tests and assessments of liver and kidney function are required. Taking this medication concurrently with other nonsteroidal anti-inflammatory drugs increases the risk of side effects, so co-administration should be avoided. Interactions may occur with certain blood pressure medications, anticoagulants, diuretics, and antidepressants, so any ongoing medications should be disclosed to healthcare professionals. Women in the early or middle stages of pregnancy must carefully consider the benefits and risks of this medication, and it should not be taken during the late stages of pregnancy. For breastfeeding mothers, it is safest not to take this medication as it may be transmitted through breast milk. Safety in pediatric patients has not been established, so its use in children is not recommended. Older adults have a higher likelihood of experiencing side effects, so extra caution is needed during administration, and their condition should be closely monitored after dosing. This medication should be kept out of reach of children, and transferring it to different containers is not advised as it may negatively affect the medication's quality.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory problems with cough and fever, jaundice (yellowing of skin or eyes), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination issues

Mild side effects

• Rash
• itching
• fever
• urticaria
• abdominal pain
• discomfort in the upper abdomen
• loss of appetite
• nausea
• vomiting
• diarrhea

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is recommended to maintain a storage temperature between 1°C and 30°C to ensure the medication's effectiveness.

Appearance

White round tablet

Package unit

30 tablets/bottle, 600 tablets/bottle