Medication info

Tustapin Tablets 5/10 mg

Prescription medicationTablet경구Expired
Ingredient · strength
Atorvastatin Calcium›10.36mg / 1 tabletAmlodipine Besylate›6.94mg / 1 tablet
Manufacturer / importer
신풍제약(주)
Appearance
White oval film-coated tablets
Packaging
30 tablets/bottle
Approval status
Expired

MFDS item code 201804289 · Approved 2018.10.30

This product's status changed to Expired on 2023.10.30. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment for hypertension and dyslipidemia improvement, and reduction of cardiovascular risk
Who takes it
Adults
Adult dose
As Amlodipine (Esamlodipine), orally administer 5 (2.5) mg once daily, and may increase to a maximum of 10 (5) mg per day depending on the patient's response. Adjust dosage appropriately according to symptoms. Atorvastatin is typically starting at 10 mg once daily, and may be increased to 20 mg or 40 mg as needed. Administer from 10 mg to 80 mg once a day, regardless of meals.

Ingredients

Manufacturer
신풍제약(주)

Efficacy & effects

Treatment for hypertension and dyslipidemia improvement, and reduction of cardiovascular risk

  • Hypertension
  • fixed occlusion of coronary arteries
  • vasospasm
  • vasoconstriction
  • myocardial ischemia
  • angina
  • coronary artery disease
  • myocardial infarction
  • stroke
  • revascularization
  • chronic stable angina
  • retinopathy
View approved original text

This tablet contains amlodipine, which is used to treat hypertension and angina, and atorvastatin, which helps reduce cholesterol levels and cardiovascular disease risk. Amlodipine dilates blood vessels to lower blood pressure and alleviates myocardial ischemia due to stable and variant angina, reducing hospitalization and revascularization risks in patients with low risk of heart failure. Atorvastatin decreases the risk of myocardial infarction, stroke, and revascularization, and is effective in reducing cardiovascular disease risk in diabetic patients and adults with a family history or multiple risk factors. It is also used to improve cholesterol and triglyceride levels in patients with hypercholesterolemia and dyslipidemia, as well as to increase HDL cholesterol levels. This medicine helps improve patients' cardiovascular health by comprehensively managing these conditions.

How to take

Adult dose

As Amlodipine (Esamlodipine), orally administer 5 (2.5) mg once daily, and may increase to a maximum of 10 (5) mg per day depending on the patient's response. Adjust dosage appropriately according to symptoms. Atorvastatin is typically starting at 10 mg once daily, and may be increased to 20 mg or 40 mg as needed. Administer from 10 mg to 80 mg once a day, regardless of meals.

Precautions

This medication should not be used in certain patients. For example, it should not be administered to patients who are allergic to this drug or similar drugs, have severely impaired liver function, are pregnant or breastfeeding, have muscle disorders, or have severe hypotension or cardiac problems. In addition, patients with very poor kidney function, elderly patients, alcoholics, and those with a history of liver disease should use this medication cautiously, and if there is a risk of muscle-related disorders, serum muscle enzyme levels should be checked before administration. During the use of this medication, blood pressure, liver function, and muscle condition should be regularly monitored, and in case of abnormal symptoms, patients should consult a physician immediately. In particular, symptoms such as muscle pain, muscle weakness, nausea, vomiting, fatigue, and rashes may occur, so caution is needed. Women who may become pregnant should use appropriate contraception while taking this medication and must discontinue use immediately if pregnancy is confirmed. It is also recommended that breastfeeding women not take this medication. This medication can interact with several other drugs, so if you are taking other medications, be sure to inform your physician or pharmacist. Caution or dosage adjustment may be necessary when used with certain antibiotics, antifungals, immunosuppressants, specific antihypertensive agents, and anticoagulants. In case of overdose, severe hypotension, cardiac issues, etc., may occur, so it is essential to seek medical attention immediately, and hemodialysis is not effective in removing this drug. The safety and efficacy of this medication in children or the elderly have not been well established, so special caution is needed for patients in these age groups. Finally, this medication should be kept out of reach of children, and it is advisable not to transfer it to another container.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), difficulty breathing, severe allergic reactions, toxic epidermal necrolysis, hepatitis, jaundice, extreme lethargy, severe skin reactions, angioedema, respiratory distress, asthma attacks, cough with fever and respiratory anomalies, yellowing of the skin or eyes (jaundice), sudden and severe headaches, seizures, confusion, visual disturbances, paralysis, significantly reduced urine output, severe generalized edema and blood

Mild side effects

  • Flushing
  • fatigue
  • edema
  • palpitations
  • dizziness
  • headache
  • drowsiness
  • abdominal pain
  • nausea
  • weakness
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  • lethargy
  • pain
  • weight gain/loss
  • hypotension
  • vasculitis
  • muscle rigidity
  • sensory impairment/paresthesia
  • peripheral neuropathy
  • fainting
  • dysgeusia
  • tremors
  • extrapyramidal disorders
  • erectile dysfunction
  • gynecomastia
  • changes in bowel habits
  • dry mouth
  • dyspepsia
  • gingival hypertrophy
  • gum overgrowth
  • pancreatitis
  • vomiting
  • hyperglycemia
  • arthralgia
  • low back pain
  • muscle cramps

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be kept in a tightly sealed container to protect it from air and moisture. It is also recommended to store it at room temperature between 1 and 30 degrees.

Appearance and packaging

Appearance

White oval film-coated tablets

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.