Depentidine Tablet 10 mg (Rabeprazole)

Adult dosage

1. Short-term treatment of gastric ulcers: The usual dose of lafutidine is 10mg orally twice daily, in the morning and before bedtime. In clinical trials in which treatment was given for up to 8 weeks, most ulcers healed within 8 weeks; however, the healing period may occasionally vary from patient to patient. 2. Short-term treatment of duodenal ulcers: The usual dose of lafutidine is 10mg orally twice daily, in the morning and before bedtime. In clinical trials in which treatment was given for up to 6 weeks, most ulcers healed within 6 weeks; however, the healing period may occasionally vary from patient to patient. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose of lafutidine is 10mg orally once daily before bedtime. In clinical trials in which treatment was given for up to 2 weeks, most lesions healed within 2 weeks; however, the healing period may occasionally vary from patient to patient. 4. Combination therapy with antibiotics for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication before anesthesia: The usual dose of lafutidine is 10mg per dose, administered orally twice (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer lafutidine 10mg per dose orally twice daily.

This medicine should not be used by patients allergic to its components. Moreover, this product contains lactose, and should not be administered to patients with a genetic disorder that prevents lactose digestion. Patients with a history of drug allergies, liver or kidney dysfunction, those undergoing dialysis, and the elderly should use this medicine cautiously. While using this drug, serious allergic reactions such as anaphylaxis may occur, thus if symptoms such as pale face, hypotension, or difficulty breathing appear, the medicine must be discontinued immediately, and proper treatment should be sought. Liver function may be adversely affected, so if liver enzyme levels rise or jaundice symptoms appear, the medication should be discontinued and a doctor consulted. Serious side effects such as agranulocytosis or thrombocytopenia, which may cause a decrease in blood cell counts, can occur. If symptoms such as sore throat, malaise, or fever arise, the use of the medication should be stopped immediately. Additionally, various side effects such as rare skin rashes, seizures, or cardiac issues have been reported, and if any abnormal symptoms occur, consult a physician. Gastrointestinal issues may include constipation, diarrhea, nausea, vomiting, abdominal bloating, loss of appetite, while central nervous system issues may include headache, insomnia, drowsiness, dizziness. Elderly patients should be closely monitored with adjustments to dosage and administration schedule due to weakened bodily functions. Dialysis patients may have increased drug concentration in the blood, and therefore should start at low dosages with caution. Pregnant women should only use this medicine when deemed necessary by a doctor and nursing women are advised against using this medication as it may be excreted in breast milk. The safety for children has not been sufficiently established, therefore it should be used in children with caution. This medicine should be kept out of reach of children and stored in its original packaging to maintain quality. If symptoms suggestive of malignant tumors or suspected gastric cancer arise, detailed examinations should be mandated before using this medication, and the drug should be discontinued if malignancy is confirmed. During treatment, the condition of the disease should be carefully monitored and alternative treatment methods should be made if no effect is observed. Routine checks of liver function, kidney function, blood tests, etc., should be done, and immediate consultation with a physician is required if abnormalities are detected.

• Shock
• anaphylaxis symptoms
• facial pallor
• hypotension
• generalized rash
• dyspnea
• liver dysfunction
• jaundice
• agranulocytosis
• pharyngitis

This medication should be stored in a tightly closed container to protect it from air and moisture. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle