Pamphain Power Soft Capsule (Naproxen)

Adult dose

1. Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis: Take 250-500mg of naproxen orally twice a day (every 12 hours). 2. Acute gout: Initial dose of 750mg of naproxen taken orally, followed by 250mg every 8 hours until the attack ceases. 3. Skeletal muscle disorders, postoperative pain, tooth extraction pain, dysmenorrhea, tendonitis, bursitis: Initial dose of 500mg of naproxen taken orally, then 250mg every 6-8 hours, ensuring total daily dose does not exceed 1,250mg. 4. Migraine: Initial dose of 750mg of naproxen taken orally. If necessary, an additional 250-500mg may be taken after 30 minutes from the initial dose. Total daily dose should not exceed 1,250mg. Adjust dosage based on age and symptoms.

This medication may cause gastrointestinal bleeding when taken by those who regularly consume more than three glasses of alcohol daily, so it is essential to consult a physician or pharmacist. It may affect the cardiovascular system and increase the risk of thrombosis, myocardial infarction, and stroke, so individuals with cardiovascular diseases or risk factors should be particularly cautious. There is a risk of serious gastrointestinal issues such as ulcers, bleeding, or perforations, especially for older adults or those with a history of ulcers, so symptoms should be monitored closely when taking this medication. Patients with peptic ulcers, severe blood disorders, liver dysfunction, heart failure, severe hypertension, and those allergic to this medication or other non-steroidal anti-inflammatory drugs like aspirin should not take this medication. Those with a history of peptic ulcers or blood disorders, liver or kidney diseases, heart dysfunction, hypertension, asthma, or allergies should use this medication cautiously and consult a doctor if any abnormal symptoms occur during use. This medication may rarely cause a variety of side effects including shortness of breath, low blood pressure, skin rashes, gastrointestinal bleeding, impaired liver function, kidney dysfunction, headaches, dizziness, rashes, etc., so if any of these symptoms occur, usage should be stopped immediately and a specialist consulted. While this medication helps relieve symptoms, it does not treat the underlying causes, so it is advisable to take the minimum effective dose for the shortest duration possible. When taken in conjunction with other medications, interactions may occur, so it is crucial to inform healthcare providers, especially when taking other non-steroidal anti-inflammatory drugs, antihypertensive medications, diuretics, anticoagulants, etc. During pregnancy, particularly in the later stages, it may pose risks to the fetus, therefore pregnant women or those who may become pregnant should avoid taking it or consult a physician. Breastfeeding women should refrain from taking this medication as it may be transmitted through breast milk and affect the baby. It is not recommended to use this medication in children, especially infants under 2 years of age, as safety has not been established. Elderly individuals are at a higher risk of side effects such as gastrointestinal bleeding, so starting with a small dose and cautious use is recommended, alongside regular health checks. Overdosage may lead to symptoms such as drowsiness, indigestion, and vomiting, so immediate medical treatment should be sought in such cases. This medication should be kept out of reach of children, and transferring it to another container may compromise its quality, so caution is advised.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with fever, blisters, peeling skin, pain in the mucous membranes of the mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), profound lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis, coma

Mild side effects

• Nausea
• abdominal discomfort
• stomach pain
• vomiting
• loss of appetite
• dyspepsia
• heartburn
• diarrhea
• constipation
• stomatitis

Drug interactions

Do not take this medication with other non-steroidal anti-inflammatory drugs and naproxen derivatives. Hydantoins, sulfonamides, sulfonylureas, propranolol and other β-blockers, ACE inhibitors (such as captopril), loop and thiazide diuretics, probenecid, aspirin, lithium, methotrexate, coumarin anticoagulants (such as warfarin), zidovudine, fluoroquinolone antibiotics (such as enoxacin).

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is crucial to maintain a storage temperature between 1 to 30 degrees Celsius at room temperature to preserve the medication's efficacy.

Appearance

A blue transparent oval soft capsule containing a colorless transparent liquid

Package unit

12 capsules/blister [(12 capsules/PTP X 1)], 30 capsules/bottle