Sirtelmi Tablet 80 mg (Telmisartan)

Adult dose

For essential hypertension, Telmisartan should be administered orally once a day at a dose of 40 mg with water, and it can be taken regardless of meals. A dose of 20 mg once daily may be effective for some patients, and if necessary, the dose may be increased to 80 mg once daily. The maximum antihypertensive effect is observed 4 to 8 weeks after starting treatment. To reduce cardiovascular disease risk, 80 mg should be administered orally once daily with water.

This drug can cause serious harm to the fetus and newborn during pregnancy; therefore, it should be discontinued immediately if pregnancy is confirmed. It should not be used by individuals with allergies to this drug or its ingredients, pregnant or possibly pregnant women, nursing mothers, individuals with severe liver disease, patients with hereditary angioedema, or diabetic patients with severely impaired renal function. Elderly patients, those with hyperkalemia, mild to moderate liver impairment, heart valve disease, ischemic heart disease, gastrointestinal disease, renal artery stenosis, or severe renal impairment should use this medication cautiously. This medication lowers blood pressure but may occasionally result in side effects such as dizziness, hypotension, angioedema, renal dysfunction, and hyperkalemia; therefore, patients should consult their doctor immediately if abnormal symptoms occur. During treatment with this drug, it is essential to regularly check potassium levels in the blood and renal function, particularly when taken in conjunction with other antihypertensive drugs or potassium supplements. It is advisable to avoid taking this medication within 24 hours before surgery, and caution should be exercised when driving or operating machinery due to the risk of dizziness or fainting. This medication contains sorbitol and is not suitable for individuals with fructose intolerance. Diabetic patients are at risk for coronary artery disease, so appropriate cardiac evaluations are necessary before starting this medication. Interactions may occur when taken with other antihypertensive agents, diuretics, lithium preparations, non-steroidal anti-inflammatory drugs (NSAIDs), therefore informing the doctor or pharmacist is essential. This medication is not recommended for nursing mothers, and its safety for children has not been established, hence it is advisable not to administer it to individuals under 18. In cases of overdose, symptoms such as hypotension, dizziness, and acute renal failure may occur, requiring immediate medical attention, with close monitoring of blood pressure and renal function. This medication should be kept out of reach of children and stored sealed until use.

Serious side effects

Hives, severe swelling (including angioedema, facial swelling, swelling of the lips, throat, larynx, and tongue), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reaction, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, severe cutaneous adverse reactions, respiratory distress, asthma attacks, cough with fever and breathing difficulties, liver dysfunction, liver disease, yellowing of the skin or eyes (jaundice)

Mild side effects

• Upper respiratory infection
• pharyngitis
• sinusitis
• urinary tract infection
• cystitis
• anemia
• thrombocytopenia
• eosinophilia
• hypersensitivity
• hyperkalemia

This drug should be stored in a tightly closed container to prevent air and moisture ingress, ideally at room temperature between 1 to 30 degrees Celsius. Proper storage ensures the maintenance of the drug's effectiveness and safe use.

Appearance

White or nearly white, double convex, round tablet

Package unit

30 tablets/box [10 tablets/blister x 3]