Medication info
Zanapham Tablet 0.125 mg (Alprazolam)

Zanapham Tablet 0.125 mg (Alprazolam)

Prescription medicationTabletOral
Ingredient · strength
Alprazolam›0.125mg / 1 tablet
Manufacturer / importer
Myungin Pharmaceutical Co., Ltd.
Appearance
Yellow oval tablet
Packaging
For domestic use - 200 tablets per bottle
Approval status
Active

MFDS item code 201803903 · Approved 2018.10.04 · Insurance code 651904650

Summary

Main use
Relief of symptoms associated with anxiety (including anxiety accompanied by depression), panic disorder, and psychosomatic disorders
Who takes it
Adults
Adult dose
Determine the dose individually to achieve the greatest benefit. The usual daily doses listed below are appropriate for most patients, but higher doses may be required. In such cases, increase the dose slowly to avoid adverse reactions. The risk of dependence may increase with dose and duration of treatment. Therefore, use the lowest effective dose for the shortest possible duration and frequently reassess the need for continued treatment. ○ Adults 1. Initiate treatment with alprazolam at 0.25-0.5㎎ per dose three times daily; the maximum dose is 4㎎ per day. In elderly patients, patients with hepatic impairment, and debilitated patients, initiate treatment at 0.25㎎ per dose two to three times daily. Reduce the dose if adverse reactions occur at the starting dose. 2. Psychosomatic disorders Administer 1.2㎎ of this medicine per day orally in 3 divided doses. If increasing the dose, gradually increase to a maximum of 2.4㎎ per day and administer orally in 3-4 divided doses. In elderly patients, initiate treatment at 0.4㎎ per dose once or twice daily; the maximum dose is 1.2㎎ per day. 3. Panic disorder Initiate treatment with 0.5㎎ of this medicine. Depending on the patient's response to treatment, increase the dose by no more than 1㎎ at intervals of 3-4 days, to an average daily dose of 5-6㎎ administered in 3-4 divided doses. When discontinuing treatment, reduce the dose by no more than 0.5㎎ every 3 days; lower doses may be required.

Ingredients

Manufacturer
Myungin Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of symptoms associated with anxiety (including anxiety accompanied by depression), panic disorder, and psychosomatic disorders

  • Anxiety disorders
  • anxiety symptoms
  • anxiety associated with depression
  • anxiety in psychosomatic disorders
  • tension
  • depression
  • sleep disorders
  • panic disorder
View approved original text

This medication is used for the treatment of anxiety disorders and for the short-term relief of anxiety symptoms. It also helps alleviate anxiety symptoms associated with depression. It is used to improve anxiety, tension, depression, and sleep disorders that occur in psychosomatic disorders such as gastric ulcers, irritable bowel syndrome, and autonomic nervous dysfunction. Finally, it is also useful for the treatment of panic disorders. It is used to alleviate and treat various mental and physical anxiety symptoms.

How to take

Adult dose

Determine the dose individually to achieve the greatest benefit. The usual daily doses listed below are appropriate for most patients, but higher doses may be required. In such cases, increase the dose slowly to avoid adverse reactions. The risk of dependence may increase with dose and duration of treatment. Therefore, use the lowest effective dose for the shortest possible duration and frequently reassess the need for continued treatment. ○ Adults 1. Initiate treatment with alprazolam at 0.25-0.5㎎ per dose three times daily; the maximum dose is 4㎎ per day. In elderly patients, patients with hepatic impairment, and debilitated patients, initiate treatment at 0.25㎎ per dose two to three times daily. Reduce the dose if adverse reactions occur at the starting dose. 2. Psychosomatic disorders Administer 1.2㎎ of this medicine per day orally in 3 divided doses. If increasing the dose, gradually increase to a maximum of 2.4㎎ per day and administer orally in 3-4 divided doses. In elderly patients, initiate treatment at 0.4㎎ per dose once or twice daily; the maximum dose is 1.2㎎ per day. 3. Panic disorder Initiate treatment with 0.5㎎ of this medicine. Depending on the patient's response to treatment, increase the dose by no more than 1㎎ at intervals of 3-4 days, to an average daily dose of 5-6㎎ administered in 3-4 divided doses. When discontinuing treatment, reduce the dose by no more than 0.5㎎ every 3 days; lower doses may be required.

Precautions

This medication is a benzodiazepine and acts as a sedative, used to treat anxiety or panic disorders. Taking this medication in combination with other narcotics or central nervous system depressants can lead to severe drowsiness, respiratory depression, decreased consciousness, or even death, so co-administration should be avoided or approached with extreme caution. This medication can lead to abuse and dependence, so it is important to strictly adhere to the prescribed dosage and regularly check the condition while taking it. If there has been a previous allergic reaction to this medication or similar medications, or if there are certain conditions (acute closed-angle glaucoma, severe myasthenia gravis, respiratory failure, severe liver failure, etc.), this medication should not be taken. Patients with weakened heart, liver, or kidney function, elderly patients, or those with brain issues need to be particularly cautious when using this medication, as they may experience severe side effects, requiring dosage adjustment and careful monitoring. This medication may cause drowsiness or reduced concentration, so activities like driving or operating dangerous machinery should be avoided. Regular testing such as liver function tests is required with long-term use, and abrupt discontinuation may cause withdrawal symptoms and seizures, so it should be tapered off gradually under a doctor's guidance. It is advisable not to take this medication during pregnancy, especially in the later stages, and if breastfeeding, caution should be taken as this medication can be passed into breast milk and affect the infant. This medication may interact with various drugs, so inform your doctor or pharmacist of any other medications being taken, especially those that influence liver metabolism, as dosage adjustments may be needed. In the case of overdose, severe drowsiness, decreased consciousness, respiratory depression, etc., may occur, requiring immediate medical attention. This medication should be kept out of the reach of children and stored in its original container to prevent misuse.

Side effects

  • Mild discomfort
  • insomnia
  • abdominal and muscle cramps
  • vomiting
  • sweating
  • tremors
  • convulsions
  • seizures
  • excitement
  • increased muscle rigidity
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  • sleep disorders
  • hallucinations
  • anxiety
  • anger
  • irritability
  • aggressive behavior
  • hostile behavior
  • hypersensitivity
  • animosity
  • obsessive thoughts
  • drowsiness
  • ataxia
  • memory impairment
  • speech disorders
  • dizziness
  • headache
  • balance disorders
  • coordination issues
  • attention disorders
  • hypersomnia
  • somnolence
  • tremors
  • amnesia
  • autonomic nervous system imbalance
  • muscle tone disorders
  • blurred vision
  • constipation
  • dry mouth
  • nausea
  • hepatitis
  • liver dysfunction
  • jaundice
  • dermatitis
  • angioedema
  • photosensitivity
  • muscle weakness
  • urinary incontinence
  • urinary retention
  • sexual dysfunction
  • irregular menstruation
  • fatigue
  • drug withdrawal syndrome
  • peripheral edema
  • weight loss
  • weight gain
  • increased intraocular pressure
  • anxiety
  • delirium
  • disorientation
  • decreased libido
  • increased libido
  • mania
  • hypomania
  • abnormal thinking
  • movement disorders
  • substance abuse
  • confusion
  • insomnia
  • neurogenic
  • syncope
  • dizziness
  • inability to sit still
  • thirst
  • diarrhea
  • increased salivation
  • tachycardia
  • palpitations
  • hypotension
  • dermatitis
  • nasal congestion
  • weight gain
  • weight loss
  • fatigue
  • coordination disorders
  • sensory disturbances
  • polyuria
  • vasomotor disorders
  • depersonalization
  • abnormal dreams
  • fear
  • warm sensation
  • decreased salivation
  • abdominal discomfort
  • chest pain
  • hyperventilation
  • upper respiratory infection
  • tinnitus
  • muscle cramps
  • muscle rigidity
  • sweating
  • rash
  • increased appetite
  • decreased appetite
  • urination disorders
  • menstrual disorders
  • erectile dysfunction
  • edema
  • urinary incontinence
  • infection
  • seizures
  • depersonalization
  • taste changes
  • double vision
  • increased bilirubin
  • elevated liver enzymes
  • jaundice
  • delirium
  • apathy
  • hyperactivity
  • dyspepsia
  • asthenia
  • chest pain
  • lethargy
  • falls
  • ataxia
  • difficulty concentrating
  • excessive sedation
  • unclear language
  • coma
  • respiratory depression

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light, so it should be stored in a container that does not allow light to enter. Additionally, it is best to store the medication at room temperature between 1°C and 30°C, not in too hot or too cold places.

Appearance and packaging

Appearance

Yellow oval tablet

Package unit

For domestic use - 200 tablets per bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.