Isome Tablet 40 mg (Esomeprazole Magnesium Hydrate)

Adult dosage

This medication should be swallowed with liquid, and should not be chewed or crushed. 1. Adults 1) Gastroesophageal Reflux Disease (GERD). - Treatment of erosive reflux esophagitis: administer 40 mg once daily for 4 weeks. If symptoms persist, continue for another 4 weeks. - Long-term maintenance therapy for recurrence prevention: 20 mg once daily. - Symptomatic treatment of gastroesophageal reflux disease without esophagitis: 1 day 1 time, 20 mg once daily.

Children's dosage

Adolescents aged 12 years and older: - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks. - Symptomatic treatment without esophagitis: 20 mg once daily. - Symptom relief.

This medication should not be administered to certain patients. Patients who are allergic to this drug or its ingredients or have had hypersensitivity reactions should not take it. Additionally, caution is needed for patients allergic to penicillin antibiotics or macrolide antibiotics when used in combination. Specifically, patients taking certain medications or nursing mothers should not take this medication. Various adverse reactions have been reported for this drug, with common symptoms including headache, abdominal pain, diarrhea, and constipation. Rarely, blood-related abnormalities, hypersensitivity reactions, hypomagnesemia, psychiatric symptoms, liver function abnormalities, and skin rashes may occur, and if symptoms appear, immediate consultation with healthcare providers is necessary. Prolonged use may mask symptoms of malignancy; therefore, if symptoms such as weight loss, vomiting, or hematemesis occur, medical consultation is required. Regular examinations are necessary for those taking the drug for more than one year. This drug suppresses gastric acid secretion, which may increase the risk of bacterial overgrowth in the gastrointestinal tract, so if diarrhea persists, inform your healthcare provider. The risk of fractures may increase, so patients at risk for osteoporosis should have periodic monitoring. This drug is not suitable for patients with certain genetic diseases, particularly those with fructose intolerance, should avoid it. There are many drug interactions; therefore, while taking this medication, it is essential to discuss any concomitant medications with a physician or pharmacist. Caution is especially required when interacting with antiviral drugs, antibiotics, anticoagulants, and anticonvulsants. The safety of this medication during pregnancy has not been fully established; thus, pregnant women should consult their physician before taking it. Breastfeeding women are advised not to take this medication. In case of overdose, there is no specific antidote, so seek immediate medical attention for appropriate treatment, and keep it out of reach of children. To maintain quality, it is advised not to transfer this drug to other containers.

Serious side effects

Urticaria, angioedema, anaphylactic reactions, shock, hypomagnesemia, hepatitis with or without jaundice, liver failure, encephalopathy, Stevens-Johnson syndrome, toxic epidermal necrolysis, acute generalized exanthematous pustulosis, drug reaction with eosinophilia and systemic symptoms (DRESS syndrome), interstitial nephritis, seizures, severe skin reactions (SJS, TEN, DRESS, AG

Mild side effects

Headache, dizziness, sensory disturbances, drowsiness, taste disorders, blurred vision, bronchospasm, abdominal pain, constipation, diarrhea, abdominal distention, nausea, vomiting, dry mouth, stomatitis, Candida infection in the gastrointestinal tract, increased liver enzymes, dermatitis, itching, rash, hair loss, photosensitivity, fracture, arthralgia, myalgia, gynecomastia, weakness, increased sweating, abdominal distension, allergic reactions, back pain, chest pain, sternal pain, facial swelling, facial flushing, fatigue, fever,

This drug should be stored in a tightly closed container, protected from air and moisture. The storage temperature should be kept between 1 to 30 degrees Celsius, avoiding extremely hot or cold places.

Appearance

Pink round film-coated tablet

Package unit

28 tablets (14 tablets/Alu-Alu×2)