Cekoxia Capsule 100 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient. It may be taken with or without food. ○ Adults 1. Osteoarthritis (degenerative arthritis) Take celecoxib 200 mg once daily, or 100 mg twice daily. 2. Rheumatoid arthritis Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS) Administer celecoxib 200 mg once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment with 400 mg per day, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment onward, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This drug increases the risk of gastrointestinal bleeding if taken by individuals who consume large amounts of alcohol daily, so it is essential to consult a doctor or pharmacist before use. This drug may increase the risk of cardiovascular diseases; therefore, it should only be used at the minimum effective dose for the shortest time necessary, and if symptoms of cardiovascular issues occur, medical attention should be sought immediately. Patients with a history of gastrointestinal issues such as perforation, ulcer, or bleeding should be particularly cautious, especially the elderly, and if any symptoms of gastrointestinal bleeding occur, immediate treatment should be sought. Individuals who have had allergic reactions to this drug or have hypersensitivity to sulfonamides, aspirin, or other non-steroidal anti-inflammatory agents should not take it. It is also unsafe for patients with severely impaired liver or kidney function, active peptic ulcers, inflammatory bowel disease, heart failure, or a history of cardiovascular diseases to use this drug. Women who are pregnant, may become pregnant, or nursing mothers should not take this drug, and women planning to become pregnant should use caution. While taking this medication, regular monitoring and testing of liver, kidney, and cardiovascular conditions are required, and if any unusual symptoms arise, a doctor should be consulted immediately. This drug can interact with various other medications; therefore, if other medications are being taken, the healthcare provider must be informed, especially while using blood pressure medications, diuretics, anticoagulants, or antidepressants. Drowsiness or dizziness may occur while taking this drug, so caution should be exercised when driving or operating machinery. Elderly patients may be at a higher risk of decreased kidney, liver, or heart function, requiring more careful observation while taking this drug. Long-term use may result in anemia or blood disorders, necessitating regular blood tests and liver and kidney function evaluations. If symptoms such as skin rash, fever, itching, or blisters appear while taking this drug, it should be stopped immediately and the patient should consult a doctor. Overdose may result in symptoms such as nausea, vomiting, drowsiness, and gastrointestinal bleeding, requiring immediate emergency treatment. This drug is not recommended for use in children and adolescents as its safety and efficacy have not been established.

Gastrointestinal bleeding, cardiovascular thromboembolic events, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tracts, ulcers, bleeding, bronchitis, sinusitis, upper respiratory infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle rigidity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmias, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcers, dental disorders, duodenal ulcers, esophageal ulcers, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, injuries, headaches, leg cramps, sensory loss, migraines, neuropathic pain, neuropathy, paresthesia, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, allergic reactions, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, malaise, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactoid reactions, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, liver failure, fulminant hepatitis, hepatic necrosis, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, minimal change disease, menstrual disorders, female infertility, chest pain, thirst, ulcerative stomatitis, gastritis, low back pain, hyperlipidemia, diabetes, weight gain, fractures, arthralgia, RA factor positive, shingles, pneumonia, dyspnea, elevated ALT, hearing loss, nosebleeds, speech disorders, laryngitis, pneumonia, hearing impairment, ear abnormalities, otalgia, hearing loss, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, hepatic necrosis, bile stasis, bile stasis hepatitis, jaundice, increased serum sodium, increased serum potassium, increased BUN, increased CPK, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, increased alkaline phosphatase, weight gain, loss of appetite, increased LDH, hypoglycemia, hyponatremia, bursitis, arthralgia, osteoarthritis, skeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, fractures, tendon rupture, pain in the back, muscle stiffness, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopathy, anemia, thrombocytopenia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, eczema, contact dermatitis, injection site reactions, skin nodules, taste disturbances, albuminuria, cystitis, hematuria, dysuria, polyuria, kidney stones, urinary incontinence, urinary tract infections, visual confusion, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis

This medication should be stored in a tightly sealed container to prevent air and moisture exposure. Additionally, it should be kept away from extreme temperatures, ideally between 15 and 30 degrees Celsius.

Appearance

A white capsule filled with white to slightly yellow powder, with a blue stripe on the upper and lower sides.

Package unit

30 capsules/bottle, 100 capsules/bottle