Medication info
Ebsimbajung 10/20 mg

Ebsimbajung 10/20 mg

Prescription medicationTablet경구
Ingredient · strength
Ezetimibe›10mg / 1 tabletSimvastatin›20mg / 1 tablet
Manufacturer / importer
(주)한국파마
Appearance
White to near-white, double convex rectangular tablet
Packaging
30 tablets (10 tablets/Alu-Alu x 3)
Approval status
Active

MFDS item code 201803738 · Approved 2018.09.17

Summary

Main use
Improvement of cholesterol and lipids in hypercholesterolemia (primary, homozygous familial) and mixed hyperlipidemia
Who takes it
Adults
Adult dose
This medication is taken once daily in the evening, regardless of meals. The dose range for patients with primary hypercholesterolemia is 10/10 mg to 10/40 mg daily, with a generally recommended starting dose of 10/20 mg daily. Patients who require less reduction in LDL cholesterol may start with 10/10 mg daily. The recommended dose for patients with homozygous familial hypercholesterolemia is 10/40 mg daily, taken once in the evening.

Ingredients

Manufacturer
(주)한국파마

Efficacy & effects

Improvement of cholesterol and lipids in hypercholesterolemia (primary, homozygous familial) and mixed hyperlipidemia

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed hyperlipidemia
  • homozygous familial hypercholesterolemia
  • atherosclerotic vascular disease due to hypercholesterolemia
  • dyslipidemia
View approved original text

This medication helps reduce elevated total cholesterol, LDL cholesterol, ApoB protein, and triglycerides in patients with primary hypercholesterolemia and mixed hyperlipidemia, and increases HDL cholesterol (the good cholesterol). It is used as an adjunct therapy, especially in patients with familial hypercholesterolemia or when dietary measures alone are insufficient. This medication is used in conjunction with an appropriate diet and is administered when dietary measures do not provide sufficient effect. It is important to identify and address causes of dyslipidemia, such as diabetes and hypothyroidism, before use. Additionally, during treatment, regular management of cholesterol and triglyceride levels contributes to reducing cardiovascular disease risk. In summary, this medication is used to improve blood lipid levels associated with hypercholesterolemia and support cardiovascular health.

How to take

Adult dose

This medication is taken once daily in the evening, regardless of meals. The dose range for patients with primary hypercholesterolemia is 10/10 mg to 10/40 mg daily, with a generally recommended starting dose of 10/20 mg daily. Patients who require less reduction in LDL cholesterol may start with 10/10 mg daily. The recommended dose for patients with homozygous familial hypercholesterolemia is 10/40 mg daily, taken once in the evening.

Precautions

This medication is helpful in reducing blood cholesterol levels. Muscle issues can occur, so if muscle pain or weakness appears, notify your doctor immediately. Especially when taking high doses or in conjunction with certain medications, the risk of myopathy or rhabdomyolysis may increase. Women who are pregnant or breastfeeding should not take this medication, and women planning to become pregnant should consult with their doctor. It is advisable not to use this medication if liver function is impaired or if there are liver diseases. Furthermore, this medication can interact with certain medications, so if taking other drugs, it is essential to inform your doctor or pharmacist. Caution is also needed for the elderly, children, and adolescents, and regular blood tests to check liver and muscle status are important. There is no specific antidote for overdose, so appropriate treatment must be given according to symptoms. When taking this medication, avoid grapefruit juice or certain medications, and consult healthcare professionals immediately if new symptoms arise.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/eye mucosa, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, thunderclap headache, seizures, confusional state, visual disturbances, paralysis, significantly reduced urine output, severe edema with increased blood pressure, anaphylaxis

Mild side effects

  • Headache
  • diarrhea
  • influenza
  • upper respiratory tract infection
  • muscle pain
  • limb pain
  • fatigue
  • nausea
  • abdominal pain
  • constipation
Show 28 more
  • dyspepsia
  • flatulence
  • itching
  • rash
  • thrombocytopenia
  • vomiting
  • dizziness
  • paresthesia
  • depression
  • cholelithiasis
  • cholecystitis
  • muscle cramps
  • arthralgia
  • lower back pain
  • cough
  • cataract
  • weakness
  • insomnia
  • mucus in stool
  • irritable bowel syndrome
  • sore throat
  • hair loss
  • decreased libido
  • sexual dysfunction
  • dizziness
  • syncope
  • sensory loss
  • blood

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to air and moisture, so it should be stored in a tightly sealed container. Additionally, it is best to store it at room temperature between 1 degree and 30 degrees Celsius. This will help maintain the medication’s effectiveness and prevent deterioration.

Appearance and packaging

Appearance

White to near-white, double convex rectangular tablet

Package unit

30 tablets (10 tablets/Alu-Alu x 3)

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.