Rosutap 20 mg (Rosuvastatin Calcium)

Adult dosage

In patients with primary hypercholesterolemia, combined hyperlipidemia, and primary dysbetalipoproteinemia, it is administered once daily at any time, regardless of meals. The initial dose is 5 mg once daily, which can be adjusted to a maintenance dose as needed. A maintenance dose of 10 mg once daily is suitable for most patients and should be adjusted based on LDL cholesterol levels and patient response at intervals of no less than 4 weeks.

This drug should not be administered to certain patients. For example, it should not be used in those with allergies to any of its components, severely impaired liver function, muscle disorders, patients taking certain immunosuppressants, those with severe renal impairment, pregnant or nursing women, and patients with genetic lactose intolerance. Caution is advised when using this drug in patients with a history of heavy alcohol use or liver disease, and regular liver function tests should be conducted. Additionally, if symptoms such as muscle pain or weakness occur, the patient should inform their doctor immediately, and patients at high risk of muscle damage should undergo regular muscle enzyme tests before and during treatment. This drug may increase blood concentration when taken with certain medications, raising the risk of muscle damage, so dosage adjustments or discontinuation may be necessary when used with specific drugs. Caution is particularly needed when combined with fibrate-class medications. Women of childbearing potential should use appropriate contraceptive methods while taking this medication, and this drug should not be used during pregnancy. It may be transmitted through breast milk; therefore, nursing mothers should also avoid using it. In case of overdose, there is no specific antidote, so treatment should be based on symptoms, and liver function and muscle enzyme levels should be monitored. Dizziness may occur during the use of this drug, so caution is advised when driving or operating machinery. While taking this drug, it is important to regularly check liver and muscle health status and consult medical personnel immediately if any abnormal symptoms arise.

Serious side effects

Allergic reactions including hives and angioedema, pancreatitis, myopathy, rhabdomyolysis, polyneuropathy, amnesia, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), immune-mediated necrotizing myopathy, jaundice, hepatitis, acute renal failure, oliguria, thrombocytopenia, increased serum creatinine, severe liver damage and/or hyperbilirubinemia, interstitial lung disease, severe allergic reactions

Mild side effects

• Headache
• dizziness
• constipation
• nausea
• abdominal pain
• itching
• rash
• myalgia
• weakness
• diarrhea

This medication should be stored in a tightly closed container to protect it from air and moisture, and it is recommended to keep it at room temperature between 1 degree and 30 degrees Celsius. This way of storage helps maintain the effectiveness of the medication and prevents degradation.

Appearance

Pink round film-coated tablets

Package unit

100 tablets/bottle, 30 tablets/bottle