Medication info

Antiphramin Lotion

OTC medicationLotion
Ingredient · strength
Methyl Salicylate›200mg / 1gL-Menthol›60mg / 1gTocopherol Acetate›5mg / 1g
Manufacturer / importer
(주)유한양행
Appearance
A white, uniform suspension with lime and mint fragrances.
Packaging
100mL/bottle, 500mL/bottle
Approval status
Active

MFDS item code 201803717 · Notified 2018.09.13

Summary

Main use
Pain relief and anti-inflammatory (e.g., musculoskeletal pain) and improvement of skin itching.
Who uses it
Adults
Adult dosage
Apply an appropriate amount to the affected area (site of the condition) 1-4 times a day.

Ingredients

Manufacturer
(주)유한양행

Efficacy & effects

Pain relief and anti-inflammatory (e.g., musculoskeletal pain) and improvement of skin itching.

  • Bruises
  • muscle pain
  • joint pain
  • fracture pain
  • back pain
  • shoulder stiffness
  • neuralgia
  • rheumatic pain
  • skin itching
  • insect bites
  • chilblains
View approved original text

This medication is used to relieve various types of pain and inflammation such as bruises, muscle pain, joint pain, and back pain. It is also effective for skin itching or insect bites and helps treat chilblains (frostbite). Thus, this drug is widely used to improve various types of pain, inflammation, and skin issues.

Dosage and Administration

Adult dosage

Apply an appropriate amount to the affected area (site of the condition) 1-4 times a day.

Precautions

This medication should not be used by individuals who are allergic to any ingredients contained in this drug. It should not be applied to mucous membranes such as the eyes, eye area, or inside the mouth, nor should it be applied to areas with eczema, dermatitis, or wounds. Individuals who have experienced allergic reactions to drugs or cosmetics, or those with a family history of allergic conditions, must consult a professional before using this medication. Patients with moist skin or skin that is chafed, those receiving treatment from a physician, or patients with circulatory diseases or diabetes should also consult a healthcare professional before use. Women who are pregnant or may become pregnant, breastfeeding women, and children under 12 should discuss with a professional before using this medication. If symptoms such as rash, redness, swelling, itching, or pain appear while using this product, use should be discontinued immediately and a professional should be consulted. Additionally, if symptoms do not improve after 5-6 days of use, it is advised to stop using the medication and consult a physician. The prescribed dosage and method of use must be strictly followed, and adult supervision is required when children are using this medication. This medication is for external use only and should never be ingested or inhaled. Care should be taken to avoid contact with the eyes, and if contact occurs, it should be rinsed immediately with clean water. When the medication comes into contact with the hands, care must be taken to avoid contact with mucous membranes, and hands that have touched the medication should be washed thoroughly. Do not cover or wrap the area where the medication has been applied, and avoid exposure to hot water or heat. Take caution as water may cause irritation to the area where the medication is applied. Individuals with sensitive skin should avoid repeated use on the same area. The presence of methyl salicylate means that symptoms of toxicity could appear if used over a wide area for an extended period of time; caution is advised in such cases. This medication should be kept out of reach of children, stored in a cool, dry place away from direct sunlight, and the cap must be closed tightly during storage. Transferring the medication to another container may lead to misuse or diminished quality, so it must be stored in its original container at all times. After use, ensure that the cap is securely closed, as leaks may stain or damage plastic, clothing, wood, and leather.

Side effects and when to seek care immediately

Mild side effects

  • Rash
  • redness (congested appearance)
  • itching
  • pain
  • swelling.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to protect it from air and moisture, and it's safest to keep it at a temperature between 1 degree and 30 degrees Celsius.

Appearance and packaging

Appearance

A white, uniform suspension with lime and mint fragrances.

Package unit

100mL/bottle, 500mL/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

  • QThe area where I applied it has swollen red.

    If you experience rash, redness, swelling, itching, or pain, stop using it immediately and consult a doctor or pharmacist. If symptoms do not subside or spread, please seek medical attention.

    Answers 1 · 2026.09.14

  • QCan I apply it on my child's sprained ankle?

    The indications include pain relief and anti-inflammatory effects for bruises, contusions, and muscle pain. However, there are no age-specific instructions in the manual, so please consult a pharmacist before using it for children, and seek medical attention if swelling is severe.

    Answers 1 · 2026.09.14

  • QCan I apply it on mosquito bites?

    Indications include skin itching and insect bites. Apply an appropriate amount to the affected area 1-4 times a day, and if swelling or pain occurs at the site, stop using it and consult a pharmacist.

    Answers 1 · 2026.09.14

For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.