Cerecoks Capsule (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be administered regardless of meals. ○ Adults 1. Osteoarthritis (degenerative arthritis) : Take celecoxib 200 mg once daily, or 100 mg twice daily. 2. Rheumatoid arthritis : Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS) : Administer celecoxib 200 mg once daily, or 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment at 400 mg daily, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea : The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment : In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may cause gastrointestinal bleeding when taken by individuals who consume large amounts of alcohol daily, so consult with a doctor or pharmacist before use. In patients with heart or vascular issues or risk factors, this medication may lead to serious thrombotic problems such as myocardial infarction or stroke, so it should be used at the minimum possible dosage and for the shortest duration. If there is a history of ulcers or bleeding in the gastrointestinal tract, the risk of gastrointestinal perforation or bleeding may increase during the use of this drug, requiring caution. This drug should not be administered to individuals with certain allergies, severe liver or kidney disease, active gastrointestinal bleeding, heart failure, or pregnant women. Those with impaired liver or kidney function, asthma, hypertension, or heart failure should use this medication cautiously, and regular monitoring by a physician may be necessary. During treatment with this drug, various side effects such as indigestion, diarrhea, abdominal pain, headache, dizziness, skin rash, hypertension, etc., may appear, so any abnormal symptoms should be reported immediately. If a rash, blistering, or itching develops, use should be discontinued immediately, and medical advice should be sought. This drug may interact with other medications, so it is essential to inform healthcare providers of any current medications. Pregnant women or those planning to become pregnant should avoid using this drug and nursing mothers should decide after consulting their physician. Elderly patients may have decreased kidney and cardiac function, so extra caution is needed when taking this medication, and dosage adjustments may be necessary. This drug has not established safety and efficacy in children and adolescents, and it is generally advised not to use it in this population. If dizziness or drowsiness occurs during treatment, driving or operating machinery should be avoided. Regular blood tests and liver and kidney function tests should be conducted during the use of this drug, and should there be any abnormal findings, healthcare providers need to be contacted immediately. In case of overdose, symptoms such as vomiting, lethargy, and gastrointestinal bleeding may occur, so immediate hospital visit is necessary, and there is no specific antidote for this drug. This drug should be stored out of reach of children and should not be transferred to another container.

Gastrointestinal hemorrhage, thrombotic reactions in the cardiovascular system, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tracts, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle rigidity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, flatulence, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, petechiae, angioedema, alopecia, bullous dermatitis, peripheral edema, facial swelling, influenza-like illness, injury, altered taste, albuminuria, cystitis, hematuria, dysuria, polyuria, nephrolithiasis, urinary incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, elevated β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis, increased serum sodium, increased serum potassium, elevated BUN, increased CPK, diabetes mellitus, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, elevated NPN, increased creatinine, increased alkaline phosphatase, weight gain, loss of appetite, elevated LDH, hypoglycemia, hyponatremia, synovial sac, arthralgia, arthropathy, skeletal abnormalities, myalgia, cervical dystonia, synovitis, tendinitis, myositis, leg cramps, fractures, tendon rupture, pain in the neck, muscle stiffness, reduced hematocrit, increased hemoglobin, petechiae, nosebleed, thrombocytopathy, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, phlebitis, contact dermatitis, injection site reactions, skin nodules, headache, leg cramps, tension headache, sensory loss, migraine, neuralgia, neuropathy, sensory disturbance, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, exacerbation of allergies, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reactions, vasculitis, angioedema, hallucinations, exacerbation of epilepsy, upper respiratory tract infection, shingles, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, moniliasis, genital moniliasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic disease of the breast, thoracic neoplasms, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, elevated ALP, positive urinary urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, vasculitis, pulmonary embolism, interstitial pneumonia, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, minimal change disease, female infertility, chest pain, anaphylaxis reactions, hallucinations, cerebral hemorrhage

This medication should be stored in a tightly closed container to prevent air and moisture from entering. It is best kept at room temperature between 15 to 30 degrees Celsius.

Appearance

An opaque white capsule containing a white to light yellow powder.

Package unit

30 capsules/bottle, 100 capsules/bottle