Renidipine Tablet (Lercanidipine Hydrochloride)

Adult dose

As Lercanidipine Hydrochloride, administer 5 to 10 mg orally once a day at least 15 minutes before a meal. The dosage may be increased to 20 mg depending on the patient's symptoms. Dosage adjustments take up to 2 weeks to respond clearly with maximum antihypertensive effect, so adjustments should be made gradually. For the elderly, dosage adjustment is not necessary, but caution is required at the start of treatment. For patients with mild to moderate liver and kidney impairment, special caution is needed at the beginning of treatment.

This drug should not be used in certain patients. For example, it should not be administered to those allergic to this drug or similar medications, pregnant or breastfeeding women, patients with heart problems, severe liver or kidney function impairment, and children and adolescents under the age of 18. Additionally, caution is advised when administering to patients with cardiac arrhythmias, mild kidney or liver function impairment, patients with a history of angina, those who consume alcohol frequently, and the elderly. When taking this medication, symptoms such as flushing of the face or swelling of the extremities may occur, and side effects such as headache, dizziness, fatigue, and indigestion may also be present. If liver function impairment is suspected, discontinue use immediately and consult a physician. Abrupt discontinuation of this medication may worsen symptoms, therefore dosing should be gradually reduced, and care should be taken to avoid dizziness or drowsiness while driving or operating machinery. This medication is metabolized by the liver, which can lead to interactions when taken with certain drugs. It is especially advised not to take with medications that inhibit or induce liver enzymes, grapefruit juice, or alcohol. Pregnant or potentially pregnant women and breastfeeding women should not take this medication, and safety has not been established for children and adolescents under 18. Special caution is required for the elderly, and in case of overdose, severe hypotension or heart problems may occur, requiring immediate medical attention. This medication should be kept out of reach of children, and caution should be observed as transferring to other containers may alter quality.

Serious side effects

Severe edema (including peripheral edema), hypotension, chest pain, angina, sweating

Mild side effects

Facial flushing, peripheral edema, palpitations, tachycardia, hypotension, chest pain, headache, dizziness, weakness, fatigue, drowsiness, neurosis, indigestion, nausea, vomiting, abdominal pain, diarrhea, increased serum levels of hepatic aminotransferases, polyuria, frequent urination, gingival hyperplasia, rash, myalgia, tremor, insomnia, dry mouth, tingling of hands, cough, abdominal bloating, erectile dysfunction, arrhythmia, sweating, skin tingling, premature contractions, rigidity of the tongue, ventricular shock

This medication should be stored in a tightly closed container to avoid exposure to air or moisture, and it is safe to store at room temperature between 1 and 30 degrees Celsius. Proper storage will maintain the drug’s effectiveness and prevent degradation.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle