Medication info

Estol Tablets 10 mg (S-Pantoprazole Sodium Trihydrate)

Prescription medicationExpired
Ingredient · strength
S-Pantoprazole Sodium Trihydrate›Strength being verified
Manufacturer / importer
Dongkuk Pharmaceutical Co., Ltd.
Appearance
Pink rectangular enteric-coated tablets
Packaging
28 tablets/bottle
Approval status
Expired

MFDS item code 201803168 · Approved 2018.07.31

This product's status changed to Expired on 2023.07.31. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of non-erosive gastroesophageal reflux disease and prevention of recurrence of reflux esophagitis
Who uses it
Adults
Adult dosage
1. Treatment of non-erosive gastroesophageal reflux disease: Administer 10mg of S-pantoprazole orally once daily before breakfast. Symptoms generally improve within 2 ~ 4 weeks, and healing is usually achieved with 4 weeks of treatment. 2. Long-term maintenance therapy to prevent recurrence of reflux esophagitis: Take 1 tablet (10mg of S-pantoprazole) once daily before breakfast. If recurrence occurs, increase the dose to 20mg of S-pantoprazole per day, then reduce it again to 10mg per day after healing.

Ingredients

Manufacturer
Dongkuk Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of non-erosive gastroesophageal reflux disease and prevention of recurrence of reflux esophagitis

  • Non-erosive gastroesophageal reflux disease
  • reflux esophagitis
View approved original text

This medication is used for the treatment of non-erosive gastroesophageal reflux disease and is suitable for long-term maintenance therapy to prevent recurrence of reflux esophagitis. It helps alleviate symptoms and prevent recurrence by regulating excessive gastric acid secretion. Therefore, it is used effectively for the treatment and prevention of disorders related to the stomach and esophagus.

Dosage and Administration

Adult dosage

1. Treatment of non-erosive gastroesophageal reflux disease: Administer 10mg of S-pantoprazole orally once daily before breakfast. Symptoms generally improve within 2 ~ 4 weeks, and healing is usually achieved with 4 weeks of treatment. 2. Long-term maintenance therapy to prevent recurrence of reflux esophagitis: Take 1 tablet (10mg of S-pantoprazole) once daily before breakfast. If recurrence occurs, increase the dose to 20mg of S-pantoprazole per day, then reduce it again to 10mg per day after healing.

Precautions

This medication should not be used in patients with moderate to severe impairment of liver or kidney function, as safety and efficacy have not been sufficiently confirmed. Patients with a history of allergic reactions to this medication, its components, or benzimidazole class drugs may experience serious allergic reactions when taking this medication and should avoid its use. This medication cannot be used with certain antiviral drugs, so patients taking such medications should avoid combination use. It is safer for women in early pregnancy or who may become pregnant, as well as nursing mothers, to avoid using this medication. Various side effects may occur during the course of treatment with this medication, particularly gastrointestinal disorders, fatigue, headache, skin rashes, and liver function abnormalities have been reported. Regular testing is important to monitor liver function and other health conditions during prolonged use. Dizziness or vision disturbances may occur, so caution is needed when driving or operating machinery. This medication can inhibit gastric acid secretion and promote bacterial overgrowth in the gastrointestinal tract; if diarrhea persists, medical consultation is necessary. Additionally, long-term use of this medication may lead to nutrient deficiencies such as vitamin B12 absorption problems or hypomagnesemia, so caution is warranted. There are many drug interactions, and patients taking other medications must inform healthcare professionals, particularly with anticoagulants, methotrexate, and other antiviral agents. Do not arbitrarily stop or change the dosage, and take the medication at the minimum dosage and for the appropriate duration as instructed by the physician. It is recommended not to use this medication in children as its safety has not been established. No specific symptoms have been reported in case of overdose, but if abnormal symptoms occur, seek medical attention immediately. This medication should not be chewed or crushed, and must be stored out of reach of children.

Side effects

Anaphylaxis, anaphylactic shock, angioedema, bronchospasm, acute interstitial nephritis, urticaria, constipation, diarrhea, gastritis, gastric polyp, hiatal hernia, loose stools, chest pain, dyspepsia, nausea, vomiting, abdominal distension, enteritis, edema, fatigue, fever, sweating, hypertension, tachycardia, eustachian tube dysfunction, dry eyes, visual disturbances, cold, elevated liver enzymes, dizziness, sensory neuropathy, drowsiness, back pain, limb pain, headache, facial pain, boil, itching, rash, nosebleed, increased creatine phosphokinase, elevated liver enzyme (AST), decreased appetite, stomatitis, nasal congestion, runny nose, sore throat, upper respiratory infection, decrease in neutrophils, skin laceration, bloody stools, numbness, increased sputum, bladder residual urine, amputation, upper abdominal pain, abdominal distension, belching, dry mouth, weakness, malaise, elevated body temperature, increased bilirubin, liver failure, jaundice, anaphylactic shock, arthralgia, myalgia, rhabdomyolysis, bone fracture, headache, blurred vision, taste disturbances, insomnia, sleep disorders, depression, hallucinations, confusion, disorientation, interstitial nephritis, pruritus, skin erythema, angioedema, mucocutaneous syndrome, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, Reiter's syndrome, photosensitivity, hyperglycemia, agranulocytosis, leukopenia, thrombocytopenia, pancytopenia, gynecomastia, hyperlipidemia, increased lipids, weight changes, hyponatremia, hypomagnesemia, elevated CK, anxiety, bronchitis, increased cough, dyspnea, flu-like symptoms, gastroenteritis, gastrointestinal disorders, tension headaches, infections, migraines, cervical pain, pain, pharyngitis, rectal disorders, rhinitis, increased AST, sinusitis, upper respiratory infection, frequent urination, urinary tract infection, allergic reactions, chills, cyst, facial swelling, generalized edema, heat sensation, hernia, laboratory test abnormalities, malaise, moniliasis, tumors, nonspecific drug reactions, ECG abnormalities, angina, arrhythmia, atrial fibrillation, coronary artery disease, congestive heart failure, bleeding, hypotension, myocardial infarction, myocardial ischemia, palpitations, retinal vascular disease, syncope, phlebitis, thrombosis, vasodilation, decreased appetite, aphthous stomatitis, colitis, duodenitis, swallowing difficulties, esophageal bleeding, esophagitis, gastric duodenal tumors, gastric duodenal bleeding, gastric duodenal moniliasis, gingivitis, halitosis, hematemesis, increased appetite, melena, oral ulcers, oral moniliasis, periodontal abscess, periodontitis, rectal bleeding, gastric ulcer, bowel irregularity, tongue discoloration, ulcerative colitis, diabetes, goiter, gallbladder pain, hyperbilirubinemia, cholecystitis, cholelithiasis, jaundice, hepatitis, elevated ALP, anemia, petechiae, eosinophilia, iron deficiency anemia, leukocytosis, thrombocytopenia, dehydration, gout, thirst, weight gain, weight loss, arthritis, bone disease, joint disease, leg cramps, bursitis, tendinitis, abnormal dream, confusion, seizures, dry mouth, verbal disorders, hyperactivity, decreased libido, restlessness, neuralgia, neuritis, neuropathy, abnormal sensations, diminished reflexes, abnormal perception, tremors, asthma, hiccups, laryngitis, breathing difficulties, pneumonia, voice changes, acne, alopecia, contact dermatitis, eczema, fungal skin infections, bleeding, herpes simplex, herpes zoster, lichen planus, papular rash, skin diseases, skin ulcers, sweating, amblyopia, cataract, hearing loss, diplopia, otalgia, paralysis, glaucoma, external otitis, tinnitus, albuminuria, balanitis, mastalgia, cystitis, menstrual irregularities, urination disorders, epididymitis, hematuria, erectile dysfunction, kidney stones, renal pain, nocturia, prostate disorders, pyelonephritis, scrotal edema, urethral pain, urethral disorders, urogenital abnormalities, vaginitis, Clostridium difficile-associated diarrhea, DRESS syndrome, systemic lupus erythematosus, cutaneous lupus erythematosus, gastric mucosal polyps

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to light and must be stored in a container that can block light. Additionally, it is important to store it at room temperature, specifically between 1 to 30 degrees Celsius, to maintain its effectiveness.

Appearance and packaging

Appearance

Pink rectangular enteric-coated tablets

Package unit

28 tablets/bottle

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Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.