Estozol Tablet 20 mg (S-Pantoprazole Sodium Trihydrate)
S-Pantoprazole Sodium Trihydrate
Prescription medication
Dongkuk Pharmaceutical Co., Ltd.
MFDS item code 201803167 · Approved 2018.07.31
This product's status changed to Expired on 2023.07.31. It may no longer be sold, so consult a doctor or pharmacist before taking it.
Treatment of moderate to severe reflux esophagitis and gastric and duodenal ulcers
This medication is primarily used for the treatment of duodenal ulcers, gastric ulcers, and moderate to severe gastroesophageal reflux disease.
1. Gastric ulcer and moderate-to-severe reflux esophagitis - The usual adult dose is 1 tablet (equivalent to 20mg of S-pantoprazole) once daily, taken with water before breakfast without chewing or crushing. - Most cases may heal within 4 weeks, although the healing period may occasionally vary from patient to patient. If not healed after the initial 4 weeks of treatment, continue treatment for another 4 weeks. - If there has been no response to other treatments in particular, the dose may be doubled (to 40mg of S-pantoprazole once daily). 2. Duodenal ulcer - The usual adult dose is 1 tablet (equivalent to 20mg of S-pantoprazole) once daily, taken with water before breakfast without chewing or crushing. - Most cases may heal within 2 weeks, although the healing period may occasionally vary from patient to patient. If not healed after the initial 2 weeks of treatment, continue treatment for another 2 weeks. - If there has been no response to other treatments in particular, the dose may be doubled (to 40mg of S-pantoprazole once daily). ◯ Do not exceed 20mg of S-pantoprazole per day in older adults or patients with renal impairment. ◯ In patients with severe liver impairment, reduce the dose to 1 tablet (equivalent to 20mg of S-pantoprazole) once every other day.
This medication should not be used with antibiotics in patients with moderate liver or kidney dysfunction. Patients who have had allergic reactions to this medication, its ingredients, or similar class drugs should not take it. This medication cannot be used with the specific antiviral agent atazanavir, so patients taking these medications should not use it. It is advisable for women in the first 3 months of pregnancy or who could become pregnant to avoid using this medication. Lactating women should also not use this medication. This medication should not be used by patients taking the specific antiviral agent rilpivirine. Since this medication contains the dye Yellow No. 5, individuals allergic to this component should exercise caution. During treatment, gastrointestinal symptoms such as constipation, diarrhea, heartburn, nausea, and vomiting may occur. General symptoms or neurological disturbances like fatigue, edema, headache, dizziness, and insomnia have also been reported. Rarely, liver dysfunction, allergic reactions, skin rashes, and blood disorders may occur, so if any unusual symptoms arise, consult a healthcare professional immediately. For long-term use (especially over 1 year), it is important to have regular check-ups to monitor liver function and overall health status. If sudden weight loss, severe vomiting, difficulty swallowing, or hematemesis occurs during treatment, it is necessary to check for serious conditions such as cancer. Particularly increased risk of fractures may occur, so caution is needed during long-term high-dose usage. Hypomagnesemia, or decreased magnesium levels in the blood, can rarely occur, necessitating periodic blood tests if used for extended periods or in conjunction with certain medications. This medication interacts with some other drugs, so if taking other medications, be sure to inform your healthcare provider. Dizziness or vision impairment may occur, so caution is advised when driving or operating machinery. It may be risky during pregnancy or lactation, so consult a medical professional before use. Safety and efficacy in children have not been established, so it should not be used in pediatric patients. When taking this medication, do not chew or crush the tablets; swallow them whole, and keep out of reach of children.
Anaphylaxis, anaphylactic shock, angioedema, bronchospasm, acute interstitial nephritis, urticaria, constipation, diarrhea, gastritis, gastric polyp, hiatal hernia, soft stools, chest pain, dyspepsia, nausea, vomiting, abdominal bloating, enteritis, edema, fatigue, fever, sweating, hypertension, tachycardia, ear-nose-throat disorders, xerophthalmia, visual disturbances, cold, elevated liver enzymes, insomnia, dizziness, neuropathy, drowsiness, lumbago, limb pain, headache, gastric pain, sore, pruritus, rash, epistaxis, elevated creatine phosphokinase, elevated liver enzymes (AST), decreased appetite, stomatitis, nasal congestion, rhinorrhea, sore throat, upper respiratory infection, neutropenia, skin laceration, abdominal pain, numbness, increased sputum, bladder retention, amputation, upper abdominal pain, distension, nausea, dry mouth, asthenia, malaise, elevated body temperature, elevated bilirubin, jaundice with or without hepatic failure, anaphylactic reaction, arthralgia, myalgia, rhabdomyolysis, bone fracture, headache, blurred vision, dysgeusia, sleep disturbance, depression, hallucinations, confusion, disorientation, interstitial nephritis, angioedema, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, Lyell's syndrome, photosensitivity, hyperglycemia, agranulocytosis, leukopenia, thrombocytopenia, pancytopenia, gynecomastia, hyperlipidemia, increased lipid levels, weight changes, hyponatremia, hypomagnesemia, elevated CK, anxiety, bronchitis, increased cough, dyspnea, flu-like symptoms, gastroenteritis, gastrointestinal disorders, tension, infection, migraine, neck pain, pain, pharyngitis, rectal disorders, rhinitis, elevated AST, sinusitis, upper respiratory infection, frequency of urination, urinary tract infection, sore, allergic reaction, chills, facial edema, generalized edema, sensation of heat, hernia, abnormal laboratory test results, malaise, moniliasis, tumor, nonspecific drug reaction, electrocardiogram abnormalities, angina pectoris, arrhythmia, atrial fibrillation, coronary artery disease, congestive heart failure, bleeding, hypotension, myocardial infarction, myocardial ischemia, palpitations, retinal vascular disease, syncope, phlebitis, thrombosis, vasodilation, increased appetite, melena, oral ulcers, periodontal abscess, periodontitis, rectal bleeding, gastric ulcer, bowel abnormalities, tongue discoloration, ulcerative colitis, diabetes, goiter, gallbladder pain, cholecystitis, cholelithiasis, jaundice, hepatitis, elevated ALP, anemia, petechiae, eosinophilia, iron deficiency anemia, leukocytosis, dehydration, gout, thirst, weight gain, weight loss, arthritis, bone disease, joint disease, leg cramps, bursitis, tendinitis, abnormal dream, confusion, convulsions, dry mouth, dysarthria, hyperactivity, decreased libido, agitation, neuralgia, neuritis, nerve disorder, paresthesia, decreased reflex, abnormal perception, tremors, asthma, hiccups, laryngitis, respiratory dysfunction, pneumonia, voice alteration, acne, alopecia, contact dermatitis, eczema, fungal dermatitis, bleeding, herpes simplex, shingles, lichenoid dermatitis, papular exanthema, skin disease, skin ulcer, sweating, amblyopia, cataract, hearing loss, diplopia, ear pain, paralysis, glaucoma, otitis externa, tinnitus, albuminuria, balanitis, mastalgia, cystitis, menstrual irregularities, dysuria, epididymitis, hematuria, erectile dysfunction, nephrolithiasis, renal pain, nocturia, prostatic disorders, pyelonephritis, scrotal edema, urethral pain, urethral disease, urological abnormalities, vaginitis, Clostridium difficile-associated diarrhea, DRESS syndrome, systemic lupus erythematosus, cutaneous lupus erythematosus, gastric polyp
Not everyone experiences these, and they can vary from person to person.
This medication should be stored in a special container protected from light, at room temperature between 1°C and 30°C. Proper storage will help maintain the medication's effectiveness over time.
Yellow rectangular enteric-coated tablet
28 tablets/bottle
Even with the same ingredient, strength, dosage form and how it is taken can differ.
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Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.
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For anything that needs medical judgment, consult a doctor or pharmacist.
This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.