Lipitan Tablets 20 mg (Atorvastatin Calcium Hydrate)

Adult dosage

For hyperlipidemia, the recommended initial dose is 10 mg once daily, and for patients requiring greater LDL cholesterol reduction, it can be initiated at 20 mg or 40 mg once daily. Generally, it is administered within a range of 10 to 80 mg once daily, with dosing individualized according to treatment goals and patient characteristics. Lipid levels should be assessed 2 to 4 weeks after the start of therapy to determine if dosage adjustments are necessary. The goal of treatment is to lower LDL cholesterol levels, so using LDL cholesterol levels during treatment initiation and response evaluation is recommended. However, if LDL cholesterol levels cannot be used, total cholesterol levels should be monitored for treatment response. For patients with homozygous familial hypercholesterolemia, the dosing regimen is 10 to 80 mg once daily, used in conjunction with other lipid-lowering therapies (e.g., LDL apheresis), or when such therapies are not possible. 2. For pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17), the recommended initial dose is 10 mg once daily, with a maximum recommended dose of 20 mg once daily (there is no clinical data on dosing this medication above 20 mg in the pediatric population). The dosage should be adjusted to meet the recommended treatment goals for each individual patient. Adjustments should be made at intervals of 4 weeks or more. ○ For patients with renal impairment: Renal disease does not affect atorvastatin plasma concentration or LDL cholesterol-lowering efficacy, so dosage adjustments are not necessary. ○ For the elderly: The efficacy and safety for patients over 70 years old are similar to those of the general adult population.

Children's dosage

The recommended initial dose for pediatric patients with heterozygous familial hypercholesterolemia (ages 10 to 17) is 10 mg once daily, with a maximum dose of 20 mg once daily. The dosage should be adjusted at intervals of at least 4 weeks.

This medication may cause muscle-related side effects, so if severe muscle pain or weakness occurs or there is a significant rise in creatine kinase levels, discontinue use immediately and consult a doctor. Do not take this medication if there is active liver disease or if liver function test values are very high. Patients with muscle diseases, pregnant women, children under 10 years old, or those taking certain medications should not use this medication. Patients with a history of alcohol abuse or liver disease, impaired renal function, hypothyroidism, and the elderly should exercise extra caution when using this medication. During treatment, liver function and muscle status should be regularly monitored, and if any unusual symptoms arise, medical personnel should be notified immediately. This medication may interact with various drugs, so if you are taking other medications, inform your doctor or pharmacist, particularly when using certain antibiotics, antifungals, antiviral agents, some antihypertensives, and fibrate class drugs. Pregnant or breastfeeding women should not take this medication, and women of childbearing age should use appropriate contraception while taking it. The elderly and patients with impaired renal function are at higher risk of myopathy and should be monitored closely during treatment. There is no specific antidote for overdose, so visit a medical institution immediately for treatment according to symptoms. Keep this medication out of reach of children and store it safely in its original container.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory issues accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, confusion, vision disturbances, paralysis, urination issues

Mild side effects

• Weakness
• fatigue
• chest pain
• peripheral edema
• tiredness
• fever
• nasopharyngitis
• hyperglycemia
• hypoglycemia
• weight gain

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is important to maintain the storage temperature between 1 and 30 degrees Celsius at room temperature to preserve the drug's efficacy for a longer period.

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle