Seviol Tablet 10/40 mg

Adult dosage

This medication should be taken once daily, one tablet, with water regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). The recommended dosing is as follows: - 5/20 mg: administered to patients whose blood pressure is not adequately controlled with monotherapy of amlodipine 5 mg or olmesartan medoxomil 20 mg. - 10/20 mg: administered to patients whose blood pressure is not adequately controlled with olmesartan medoxomil 20 mg monotherapy.

Children's dosage

The safety and efficacy in pediatric patients under 18 years of age have not been established.

This medication can cause serious harm to the fetus and newborn during the second and third trimesters of pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. It should not be used in individuals who are allergic to any of the ingredients, are pregnant or breastfeeding, have severe liver disease, aortic stenosis, biliary obstruction, are undergoing renal dialysis, are in shock, certain diabetic patients, and patients with moderate to severe renal impairment. Blood pressure should be monitored carefully in patients with low blood pressure due to dehydration or electrolyte deficiency, particularly in the early stages of treatment, as their blood pressure may drop too low. If hypotension occurs, appropriate measures should be taken. Due to the risk of rapid vasodilation leading to hypotension, caution should be taken in patients with severe aortic stenosis. Patients with severe obstructive coronary artery disease may have an increased risk of angina or myocardial infarction when taking this medication, warranting extra caution. Use with caution in patients with heart failure, as renal function may deteriorate and lead to renal failure, requiring regular monitoring. Patients with reduced liver function may be affected by the metabolism of this drug, necessitating dosage adjustments and careful supervision. While on this medication, regular checks of blood pressure, renal function, electrolyte levels, etc., are essential, especially due to the risk of hyperkalemia, necessitating careful monitoring of potassium levels. This medication may interact with other antihypertensive agents or specific medications. If you are taking other medications, make sure to inform your healthcare provider. Breastfeeding women are advised to stop either breastfeeding or taking this medication, as it may pass into breast milk and cause side effects in infants. The safety and efficacy in children under 18 years of age have not been established, so use is not recommended. The elderly may experience altered effects and side effects due to decreased renal and liver function and should start with a low dose and be treated with caution. In case of overdose, there may be a drop in blood pressure and cardiac function abnormalities, and immediate medical attention is required, with close observation of blood pressure and cardiac function. This medication should be stored away from direct sunlight and moisture, in a tightly closed container, and should not be transferred to other containers.

Serious side effects

Hives, severe swelling (edema), polyuria, angioedema, liver abnormalities (jaundice and increased liver enzymes), severe skin reactions (hair loss, itching, hives, toxic epidermal necrolysis), severe rash accompanied by high fever, blisters, skin peeling, pain in oral/eye mucosa, difficulty breathing, asthma attacks, sudden severe headache, worsening stroke, seizures, confusion, visual disturbances, severe hypertension.

Mild side effects

• Dizziness
• headache
• drowsiness
• paresthesia
• palpitations
• cough
• nausea
• vomiting
• indigestion
• diarrhea

This medication should be stored in a tightly closed container to avoid exposure to air or moisture. It is important to maintain a storage temperature between 1 to 30 degrees Celsius.

Appearance

Reddish-brown round film-coated tablets

Package unit

30 tablets (10 tablets/PTP x 3)