Medication info
Stofujung 10mg (Lafutidine)

Stofujung 10mg (Lafutidine)

Prescription medicationTabletOral
Ingredient · strength
Lafutidine›10mg / 1 tablet
Manufacturer / importer
Bionex Co., Ltd.
Appearance
White round film-coated tablets
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 201802817 · Approved 2018.07.05 · Insurance code 643104940

Summary

Main use
Treatment of gastrointestinal disorders (e.g., ulcers and gastritis), pre-anesthetic medication, and combination therapy for eradication
Who takes it
Adults
Adult dose
1. Short-term treatment of gastric ulcers: The usual dose is 10 mg of lafutidine orally twice daily, in the morning and at bedtime. In clinical trials with treatment for up to 8 weeks, most ulcers healed within 8 weeks, although healing time may vary among patients. 2. Short-term treatment of duodenal ulcers: The usual dose is 10 mg of lafutidine orally twice daily, in the morning and at bedtime. In clinical trials with treatment for up to 6 weeks, most ulcers healed within 6 weeks, although healing time may vary among patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10 mg of lafutidine orally once daily at bedtime. In clinical trials with treatment for up to 2 weeks, most lesions healed within 2 weeks, although healing time may vary among patients. 4. Concomitant antibiotic therapy in patients with peptic ulcer disease infected with Helicobacter pylori: Administer lafutidine 20 mg, clarithromycin 500 mg, and amoxicillin 1000 mg twice daily for 7 or 14 days. 5. Premedication for anesthesia: The usual dose is 10 mg of lafutidine per dose, administered orally twice (at bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer lafutidine 10 mg per dose orally twice daily.

Ingredients

Manufacturer
Bionex Co., Ltd.

Efficacy & effects

Treatment of gastrointestinal disorders (e.g., ulcers and gastritis), pre-anesthetic medication, and combination therapy for eradication

  • Gastric ulcers
  • duodenal ulcers
  • lesions of the gastric mucosa due to acute gastritis and chronic gastritis
  • peptic ulcers
  • gastroesophageal reflux disease
View approved original text

This medication is used to treat peptic ulcers such as gastric ulcers and duodenal ulcers. It also improves gastric mucosal damage caused by acute and chronic gastritis and is administered in combination with antibiotics for patients with peptic ulcers caused by Helicobacter pylori infection. It is also used for preoperative or anesthetic administration and helps relieve symptoms of gastroesophageal reflux disease. Overall, it is used to effectively treat and improve various conditions related to gastrointestinal diseases.

How to take

Adult dose

1. Short-term treatment of gastric ulcers: The usual dose is 10 mg of lafutidine orally twice daily, in the morning and at bedtime. In clinical trials with treatment for up to 8 weeks, most ulcers healed within 8 weeks, although healing time may vary among patients. 2. Short-term treatment of duodenal ulcers: The usual dose is 10 mg of lafutidine orally twice daily, in the morning and at bedtime. In clinical trials with treatment for up to 6 weeks, most ulcers healed within 6 weeks, although healing time may vary among patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10 mg of lafutidine orally once daily at bedtime. In clinical trials with treatment for up to 2 weeks, most lesions healed within 2 weeks, although healing time may vary among patients. 4. Concomitant antibiotic therapy in patients with peptic ulcer disease infected with Helicobacter pylori: Administer lafutidine 20 mg, clarithromycin 500 mg, and amoxicillin 1000 mg twice daily for 7 or 14 days. 5. Premedication for anesthesia: The usual dose is 10 mg of lafutidine per dose, administered orally twice (at bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer lafutidine 10 mg per dose orally twice daily.

Precautions

This medication should not be used by individuals who are allergic to any of its ingredients. This medication contains lactose; therefore, patients with genetic disorders that prevent lactose digestion should not take this medication. Use with caution in patients with a history of allergic reactions, impaired liver or kidney function, patients undergoing dialysis, and the elderly. If symptoms such as pallor of the face, low blood pressure, or difficulty breathing occur during treatment, discontinue use immediately and seek medical assistance. Regularly check liver function, as abnormalities or jaundice may occur; stop use if any issues arise. There may be a decrease in white blood cells or platelets, leading to symptoms such as sore throat, malaise, or fever; discontinue use immediately and consult healthcare professionals if these symptoms occur. Rarely, severe side effects such as skin rashes, convulsions, or heart problems may occur, so consult a doctor immediately if abnormal symptoms appear. Gastrointestinal side effects may include constipation, diarrhea, nausea, vomiting, abdominal distension, and loss of appetite, while central nervous system effects may include headache, insomnia, drowsiness, and dizziness. Because elderly patients may have decreased body function, dosage and interval should be adjusted, and their condition should be closely monitored. In dialysis patients, the drug concentration in the blood may increase, so it should be administered cautiously starting from a low dose. Pregnant women should only use this medication if the physician assesses that the benefits of treatment outweigh the risks; breastfeeding women should avoid this medication as it may be excreted in breast milk. Safety has not been established for children, so its use is not recommended. Keep this medication out of the reach of children and store it in its original container to prevent misuse or degradation of quality. This medication may mask symptoms of malignant tumors, so if symptoms such as weight loss, recurrent vomiting, or hematemesis occur, thorough examination is essential. If malignant gastric cancer is confirmed, treatment should be discontinued. Patients' conditions should be carefully monitored during treatment and alternative methods should be considered if therapeutic effects are lacking. The risk of side effects may increase with long-term or excessive use, so this medication should only be taken according to a physician's instructions.

Side effects

  • Shock
  • symptoms of anaphylaxis
  • facial pallor
  • low blood pressure
  • generalized rash
  • difficulty breathing
  • liver dysfunction
  • jaundice
  • agranulocytosis
  • pharyngitis
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  • systemic fatigue
  • fever
  • thrombocytopenia
  • pancytopenia
  • aplastic anemia
  • seizures
  • interstitial nephritis
  • Stevens-Johnson syndrome
  • Rea syndrome
  • rhabdomyolysis
  • heart block
  • heart failure
  • constipation
  • diarrhea
  • hard stools
  • nausea
  • vomiting
  • abdominal distension
  • loss of appetite
  • headache
  • insomnia
  • drowsiness
  • reversible confusional state
  • hallucinations
  • consciousness disturbance
  • dizziness
  • fever
  • heat sensation
  • facial flushing
  • leukocytosis
  • eosinophilia
  • leukopenia
  • erythrocytopenia
  • decreased hematocrit
  • elevated ALT
  • elevated AST
  • elevated Al-P
  • elevated γ-GTP
  • elevated T-Bil
  • elevated LDH
  • elevated TTT
  • abnormal urine protein
  • elevated BUN
  • elevated serum uric acid
  • elevated Cl
  • delayed menses
  • elevated Na
  • decreased K
  • gynecomastia
  • edema
  • fatigue
  • glossitis
  • headache
  • urticaria
  • skin rash
  • abdominal pain
  • dyspepsia
  • enteritis
  • gastric ulcer
  • erosive gastritis
  • duodenitis
  • bloating
  • rhinopharyngitis
  • upper respiratory tract infection
  • bronchopneumonia
  • tinea
  • oral pharyngalgia
  • oral pharyngeal discomfort
  • wet cough
  • fatigue
  • chest pain
  • limb pain
  • arthralgia
  • neck pain
  • pruritus
  • acne
  • contusion
  • insomnia
  • non-alcoholic fatty liver hepatitis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture, at room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain the medication's efficacy for a longer period.

Appearance and packaging

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.