New Olmesartan 40mg Tablet (Olmesartan Medoxomil)

Adult dosage

For adults, the recommended initial dose is 10mg once daily, with or without food. If blood pressure is not adequately controlled, the dose may be increased to 20mg once daily, and if additional blood pressure reduction is needed, the maximum dose can be raised to 40mg once daily. The antihypertensive effect appears within 2 weeks after starting treatment, with maximum effect occurring around 8 weeks. If blood pressure is not controlled with this medication alone, it may be combined with thiazide diuretics such as hydrochlorothiazide.

Children's dosage

Safety and efficacy in children have not yet been established, so no dosage has been determined.

This medication can cause serious harm or death to the fetus or newborn if administered to women in the second and third trimesters of pregnancy, therefore, it must be discontinued immediately upon confirmation of pregnancy. Patients who are allergic to any component of this medication, pregnant or breastfeeding women, patients undergoing kidney dialysis, those with severe liver dysfunction, patients with biliary obstruction, and individuals with certain hereditary lactase deficiency should not take this medication. Patients with reduced blood volume or sodium may experience hypotensive symptoms initially upon starting this medication, so caution is required, and their condition should be closely monitored at the start of treatment. This medication can affect kidney function, thus patients with impaired kidney function should have their serum potassium and creatinine levels regularly checked, especially in kidney transplant recipients or those with severe kidney disease, where its use is not recommended. There is a risk of hyperkalemia, so patients with heart failure or kidney dysfunction should carefully monitor their blood potassium levels. This medication should be used with caution in patients with aortic or mitral stenosis, obstructive or hypertrophic cardiomyopathy, and may be less effective in patients with primary aldosteronism. Dizziness can occur during treatment, so it is advisable to avoid driving or operating dangerous machinery. Side effects such as dizziness, headache, back pain, cough, and others may occur, and rarely adverse reactions such as chest pain, swelling, abdominal pain, hyperkalemia, and liver dysfunction have been reported. Chronic diarrhea and weight loss may accompany chronic malabsorption syndrome-like intestinal disorders, so if these symptoms occur during treatment, consult a physician immediately. Caution is required when taking alongside potassium-sparing diuretics or potassium supplements as blood potassium levels may dangerously rise. When taken with other antihypertensives, the blood pressure-lowering effect may increase, so it should be taken according to a doctor's instructions. The use of lithium preparations concurrently may lead to elevated lithium levels and toxicity, so it is advisable not to take them together. When taken with non-steroidal anti-inflammatory drugs, there is a risk for kidney function deterioration, so renal function should be monitored during treatment. Simultaneous use of this medication with angiotensin-related drugs may increase the risk of hypotension, hyperkalemia, and renal dysfunction, so the patient's condition should be closely monitored. During pregnancy, this medication should be discontinued as soon as possible for the health of the fetus, and fetal condition should be routinely checked if necessary. Breastfeeding women should consider the possibility of this medication being excreted in breast milk, which could lead to adverse reactions in the infant, necessitating the consideration of stopping breastfeeding or discontinuing the medication. Safety and efficacy in children have not yet been established, so it is best not to administer this drug to children. Elderly patients may have an increased drug concentration in the body, requiring dosage adjustment and monitoring of their condition. In the case of overdose, symptoms such as hypotension, palpitations, and bradycardia may appear, and immediate contact with healthcare professionals is required for appropriate treatment.

Serious side effects

• Hives
• severe swelling (angioedema)
• chest pain
• angioedema
• anaphylactic reactions
• hives
• hair loss
• acute renal failure
• elevated blood creatinine
• autoimmune hepatitis

Mild side effects

• Dizziness
• back pain
• bronchitis
• increased creatine phosphokinase
• diarrhea
• headache
• hematuria
• hyperglycemia
• hypertriglyceridemia
• influenza-like symptoms

This medication can be sensitive to air and moisture, so it should be stored in a tightly closed container. The recommended storage temperature is between 1 and 25 degrees Celsius at room temperature. Proper storage can maintain the effectiveness of the medication for a longer time.

Appearance

White oblong film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle