Biphen Soft Capsules 300 mg (Dexibuprofen)

Adult dose

As dexibuprofen, 300 mg orally 2 to 4 times a day. However, do not exceed 1,200 mg of dexibuprofen in one day.

This medicine may pose a risk of gastrointestinal bleeding in individuals who regularly consume more than 3 alcoholic drinks daily; therefore, consulting a doctor or pharmacist is necessary. This medicine can affect the cardiovascular system, so individuals at risk for heart disease or stroke should be especially cautious and carefully observe for any symptoms in consultation with a doctor. During the use of this medicine, there is a possibility of serious gastrointestinal issues such as gastrointestinal bleeding, ulcers, and perforations, so if symptoms do arise, medical consultation is required immediately. People with specific conditions such as gastric ulcers or bleeding, severe liver or kidney dysfunction, heart failure, or hypertension should avoid taking this medicine. Taking this medicine alongside aspirin or other non-steroidal anti-inflammatory drugs may increase the risk of gastrointestinal adverse reactions and cardiovascular risk, so such combinations should be avoided. During the use of this medicine, breastfeeding should be suspended or discussed with a doctor, and caution is needed while driving or operating machinery due to possible dizziness or fatigue. Individuals with a history of blood abnormalities, liver dysfunction, kidney dysfunction, hypertension, hypersensitivity, elderly individuals, or children should discuss the medication with a healthcare provider before taking it. This medicine may interact with several other drugs, so inform your doctor or pharmacist if you are taking other medications, especially when used with anticoagulants, diuretics, lithium, or immunosuppressants. If symptoms such as severe allergic reactions, skin rashes, liver function abnormalities, kidney problems, difficulty breathing, severe headaches, etc. occur during treatment, discontinue use immediately and consult a healthcare provider. Pregnant women, especially after six months of pregnancy, should avoid taking this medicine or consult with a doctor due to potential effects on the fetus. This medicine should be used at the lowest effective dose for the shortest duration, and regular blood tests, along with liver and kidney function tests, are required for long-term use. In the case of overdose, seek medical attention immediately for appropriate treatment, and store it out of reach of children, avoiding direct sunlight and moisture by keeping it in a cool place.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, paleness, severe rash with high fever, blisters, peeling skin, pain in mouth/eye mucous membranes, difficulty breathing or shortness of breath, asthma attacks, respiratory difficulties accompanied by cough and fever, jaundice, marked lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, vision changes, paralysis, urination problems

Mild side effects

• Dizziness
• fatigue
• headache
• anxiety
• restlessness
• confusion
• depression
• aseptic meningitis
• mental disorders
• irritability

Drug interactions

Do not take this medicine with aspirin, other non-steroidal anti-inflammatory drugs, or high doses of methotrexate. Corticosteroids, alcohol, digoxin, phenytoin, probenecid, sulfinpyrazone, sulfonylureas, ACE inhibitors or angiotensin II receptor antagonists, diuretics, lithium, coumarin anticoagulants, baclofen, immunosuppressants (cyclosporine, tacrolimus, sirolimus), thrombolytics, or antiplatelet agents should be used with caution.

This medicine should be stored in a tightly closed container to avoid exposure to air or moisture. It is recommended to maintain storage temperatures between 1 and 30 degrees Celsius at room temperature.

Appearance

A light turquoise transparent oval soft capsule filled with a colorless transparent liquid

Package unit

10 capsules/box [10 capsules/PTP x1]