Medication info
Anipen Tablet 400 mg (Dexibuprofen)

Anipen Tablet 400 mg (Dexibuprofen)

Prescription medicationTabletOral
Ingredient · strength
Dexibuprofen D.C.›400mg / 1 tablet
Manufacturer / importer
Ahn Gook Pharmaceuticals Co., Ltd.
Appearance
Pink oblong film-coated tablet
Packaging
30 tablets/bottle, 500 tablets/bottle
Approval status
Active

MFDS item code 201802579 · Notified 2018.06.20 · Insurance code 650204900

Summary

Main use
Adjunctive treatment of joint and spinal disorders, symptoms after trauma or surgery (pain, swelling, etc.), and infections
Who takes it
Adults
Adult dose
○ Adults: Administer 400 mg of dexibuprofen orally 2~3 times daily. Do not exceed 1,200 mg of dexibuprofen per day.

Ingredients

Manufacturer
Ahn Gook Pharmaceuticals Co., Ltd.

Efficacy & effects

Adjunctive treatment of joint and spinal disorders, symptoms after trauma or surgery (pain, swelling, etc.), and infections

  • Chronic polyarthritis
  • rheumatoid arthritis
  • osteoarthritis
  • ankylosing spondylitis
  • painful swelling
  • inflammation
  • pain
  • fever
View approved original text

This medication is effective for inflammatory joint diseases such as chronic polyarthritis, rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It also helps relieve pain, swelling, and inflammation resulting from trauma or surgery. Additionally, it aids in the treatment of infections accompanied by inflammation, pain, and fever. These effects contribute to alleviating symptoms and improving the quality of life for patients.

How to take

Adult dose

○ Adults: Administer 400 mg of dexibuprofen orally 2~3 times daily. Do not exceed 1,200 mg of dexibuprofen per day.

Precautions

People who regularly consume more than 3 drinks of alcohol per day should consult a doctor or pharmacist before taking this medication. Users with a high alcohol consumption may increase the risk of gastrointestinal bleeding when taking this medication. This medication may increase the risk of cardiovascular disease, so those at risk for heart disease or stroke should exercise particular caution. Even without a history of cardiovascular disease, patients should closely monitor for cardiovascular symptoms while taking this medication. Patients with hypertension, heart failure, or ischemic heart disease should use this medication carefully and avoid high doses. As a non-steroidal anti-inflammatory analgesic, this medication may increase the risk of gastrointestinal adverse reactions such as bleeding, ulcers, and perforations. Especially elderly patients or those with a history of gastrointestinal diseases should be more cautious about gastrointestinal adverse reactions. If symptoms of gastrointestinal bleeding or pain occur, consult a doctor immediately. This medication should not be taken if certain conditions exist, such as gastrointestinal ulcers, bleeding, severe liver or kidney impairment, severe heart failure, or severe hypertension. Those with an allergy to aspirin or other non-steroidal anti-inflammatory drugs should not take this medication. Pregnant women over 6 months should refrain from taking this medication, and women who are pregnant or planning to become pregnant should consult a doctor. It is recommended not to take other NSAIDs, high-dose methotrexate, or aspirin concurrently while taking this medication. Patients should be cautious about dizziness or drowsiness when driving or operating machinery. If breastfeeding, consider discontinuing breastfeeding or the medication since it may pass into breast milk and cause adverse reactions in the infant. People with blood abnormalities, liver or kidney dysfunction, hypertension, heart failure, or a history of allergies should consult a doctor before taking this medication. If severe skin rashes, breathing difficulties, itching, or swelling occur while taking this medication, stop immediately and consult a doctor. Regular blood tests and liver and kidney function tests should be conducted during long-term use, and any abnormal symptoms should be reported to a doctor promptly. This medication may affect the fetus during pregnancy, so it should be used cautiously during this period, and especially after 20 weeks of pregnancy, the minimum effective dose for the shortest duration is recommended. In case of overdose, seek medical attention immediately, and store out of reach of children in a cool and dry place, avoiding direct sunlight.

Side effects

Gastrointestinal bleeding, serious cardiovascular thrombotic reactions, myocardial infarction, stroke, bleeding from the stomach or intestines, ulcers, perforation, dyspepsia, abdominal distension, heartburn, epigastric pain, diarrhea, constipation, loss of appetite, nausea, vomiting, abdominal pain, stomach discomfort, esophagitis, esophageal stricture, exacerbation of diverticulitis, nonspecific hemorrhagic colitis, ulcerative colitis, Crohn's disease, peptic ulcer, gastrointestinal bleeding, perforation, blood in stool, gastritis, pancreatitis, dry mouth, stomatitis, erythema multiforme, systemic lupus erythematosus, hair loss, angioedema, mucocutaneous syndrome, toxic epidermal necrolysis, eosinophilia, drug rash with systemic syndrome, acute generalized exanthematous pustulosis, rash, hives, itching, purpura, asthma attack, eczema, anaphylactic reaction, photosensitivity reaction, jaundice, elevated ALT, elevated AST, elevated ALP, liver dysfunction, hepatitis, rhinitis, bronchospasm, acute pneumonia, neglect, cancer spread, visual impairment, hearing loss, tinnitus, taste disturbance, fatigue, drowsiness, headache, dizziness, anxiety, restlessness, confusion, depression, aseptic meningitis, mental disorder, agitation, excitement, spatial disorientation, reversible toxic amblyopia, hypotension, hypertension, palpitations, acute renal failure, oliguria, hematuria, urinary protein, elevated BUN, elevated serum creatinine, hyperkalemia, decreased urine output, generalized edema, shortness of breath, lethargy, renal papillary necrosis, nephrotic syndrome, interstitial nephritis, peripheral edema, acute pulmonary edema, fluid retention, Kohnis syndrome, decreased reproductive capacity in women, periorbital edema, fatigue, fever, nosebleed, exacerbation of inflammation, crying out, facial edema, dyspepsia, pruritus, anaphylactic shock, rash, headache

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture. The storage temperature should be maintained between 1 and 30 degrees Celsius. This ensures the effectiveness of the drug is preserved for a longer time and prevents deterioration.

Appearance and packaging

Appearance

Pink oblong film-coated tablet

Package unit

30 tablets/bottle, 500 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.