Medication info
Uphebrin Tablets (Propiverine Hydrochloride)

Uphebrin Tablets (Propiverine Hydrochloride)

Prescription medicationTabletOral
Ingredient · strength
Propiverine Hydrochloride›20mg / 1 tablet
Manufacturer / importer
Mothers Pharmaceutical Co., Ltd.
Appearance
White round film-coated tablets
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201802565 · Approved 2018.06.20 · Insurance code 622803180

Summary

Main use
Relief of overactive bladder (e.g., urgency and frequency) and urinary frequency and incontinence caused by bladder disorders
Who takes it
Adults
Adult dose
Adults: The usual dose is 20 mg of propiverine hydrochloride orally once daily after a meal. The dose may be adjusted according to symptoms. If the effect is insufficient and there are no safety concerns, the dose may be increased to 20 mg twice daily.

Ingredients

Manufacturer
Mothers Pharmaceutical Co., Ltd.

Efficacy & effects

Relief of overactive bladder (e.g., urgency and frequency) and urinary frequency and incontinence caused by bladder disorders

  • Frequency
  • incontinence
  • neurogenic bladder
  • neurogenic frequency
  • unstable bladder
  • bladder irritative conditions
  • chronic cystitis
  • chronic prostatitis
  • urinary urgency
  • urgent incontinence
View approved original text

This medication is used to improve urinary frequency and incontinence caused by bladder irritative conditions such as neurogenic bladder, neurogenic frequency, unstable bladder, chronic cystitis, or chronic prostatitis. It is also effective for symptoms of urinary urgency, frequent urination, and urgent incontinence caused by overactive bladder. It effectively manages these symptoms to enhance the quality of life for patients.

How to take

Adult dose

Adults: The usual dose is 20 mg of propiverine hydrochloride orally once daily after a meal. The dose may be adjusted according to symptoms. If the effect is insufficient and there are no safety concerns, the dose may be increased to 20 mg twice daily.

Precautions

This medicine should not be used in certain patients. It is contraindicated in patients with allergies to this medication or its components, gastrointestinal obstruction or deteriorated gastrointestinal function, difficulty in urination, angle-closure glaucoma, myasthenia gravis, serious heart disease, toxic megacolon or ulcerative colitis, moderate to severe liver dysfunction, and a history of arrhythmia. Additionally, it should be used with caution in patients with urinary difficulties or liver and kidney dysfunction, Parkinson's disease, hyperthyroidism, elderly patients, autonomic neuropathy, coronary artery disease, congestive heart failure, tachycardia, benign prostatic hyperplasia, cerebral sclerosis, gastroesophageal reflux disease, and glaucoma. This medication can cause various adverse reactions in the central nervous system, digestive system, circulatory system, blood, urinary system, skin, eyes, liver, and musculoskeletal system, so if any symptoms appear, treatment should be stopped immediately, and a doctor should be consulted. During treatment, patients should check for diseases that exhibit similar symptoms such as bladder cancer, prostate cancer, urinary tract infections, urinary stones, and tumors, and those with lower urinary tract obstruction should treat that condition first. The medication may cause drowsiness, dizziness, and accommodation disorders, so driving or operating hazardous machinery should be avoided. Caution should be exercised when taken with anticholinergics, tricyclic antidepressants, phenothiazine drugs, and MAO inhibitors. It is advisable not to administer this medication to pregnant women or those who might become pregnant, breastfeeding women, and children, and elderly patients should start at a lower dose considering liver and kidney function decline. In case of overdose, symptoms such as mental confusion, seizures, gait disturbance, paralytic ileus, urinary retention, and cardiac abnormalities may occur, necessitating immediate emergency treatment. This medication should be kept out of reach of children, and transferring it to other containers should be avoided to prevent accidents and degradation of quality.

Side effects

  • Hallucinations
  • Delirium
  • Paralytic Ileus
  • Severe Constipation
  • Abdominal Distension
  • Palpitations
  • Ectopic Beats
  • Bradycardia
  • QT Prolongation
  • Ventricular Tachycardia
Show 73 more
  • Atrioventricular Block
  • Thrombocytopenia
  • Increased BUN
  • Elevated Serum Creatinine
  • Urinary Retention
  • Stevens-Johnson Syndrome
  • Fever
  • Erythema
  • Itching
  • Conjunctival Injection
  • Stomatitis
  • Increased Intraocular Pressure
  • Acute Angle-Closure Glaucoma Attack
  • Nausea
  • Headache
  • Ocular Pain
  • Visual Impairment
  • Liver Dysfunction
  • Jaundice
  • Myalgia
  • Weakness
  • Elevated CK
  • Increased Myoglobin
  • Rhabdomyolysis
  • Thirst
  • Constipation
  • Abdominal Pain
  • Nausea
  • Vomiting
  • Dyspepsia
  • Diarrhea
  • Loss of Appetite
  • Stomatitis
  • Glossitis
  • Dysuria
  • Postvoid Residual Urine
  • Loss of Urge
  • Dizziness
  • Headache
  • Numbness
  • Drowsiness
  • Insomnia
  • Tremors
  • Altered Consciousness
  • Parkinsonian Symptoms
  • Dyskinesia
  • Hypotension
  • Hypertension
  • Chest Pain
  • Hypersensitivity
  • Itching
  • Rash
  • Urticaria
  • Control Disorders
  • Dry Eye Syndrome
  • Elevated AST
  • Elevated ALT
  • Increased ALP
  • Elevated BUN
  • Elevated Creatinine
  • Leukopenia
  • Fatigue
  • Lethargy
  • Edema
  • Weakness
  • Dysgeusia
  • Low Back Pain
  • Hoarseness
  • Sputum
  • Agitation
  • Fever due to Reduced Sweat Secretion
  • Weakness
  • Pharyngitis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture. It is best to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance and packaging

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

No questions yet.

For anything that needs medical judgment, consult a doctor or pharmacist.

Related searches

Search tags

Suggested searches

This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.