Clocover Tablet (Clopidogrel Sulfate)

Adult dose

1. For patients with ischemic stroke, myocardial infarction, or peripheral artery disease, administer 75 mg of clopidogrel orally once daily. 2. For patients with acute coronary syndrome, start with a loading dose of 300 mg once daily on the day of treatment initiation, followed by a maintenance dose of 75 mg once daily. In this case, aspirin 75 – 325 mg should be administered once daily together. 3. For patients with atrial fibrillation

This medication prevents platelet aggregation and inhibits blood clotting. Before taking this medication, consult your doctor if you have a genetic deficiency in certain enzymes, as this may reduce the drug's effectiveness. Additionally, it is advisable not to take it with medications that activate certain enzymes, as this may increase drug concentration and the risk of bleeding. This medication should not be taken by those with certain diseases or drug hypersensitivity, those with bleeding, severe liver impairment, those who are breastfeeding, and those with lactose intolerance. Patients at risk of bleeding should use this medication cautiously, and if signs of bleeding appear, they should consult a doctor immediately. Patients scheduled for surgery should discontinue this medication 5-7 days prior to the procedure and also exercise caution when taking it with other medications that carry a bleeding risk. Long-term use may result in side effects such as bleeding, reduction in blood cell counts, gastrointestinal symptoms, and skin rashes, so any unusual symptoms should be reported to healthcare personnel. Pregnant women should only use it when necessary, considering the potential impact on the fetus, and should be cautious due to increased bleeding risk during delivery. If breastfeeding, it is important to consult a doctor regarding whether to continue use, as the drug may be transmitted in breast milk. The safety and efficacy in children have not been established, and elderly patients may require dose adjustments and careful monitoring due to increased bleeding risk associated with diminished bodily functions. In case of overdose, prolonged bleeding time and bleeding complications may occur, and since there are currently no antidotes for this medication, treatment such as platelet transfusion may be necessary in case of bleeding. This medication should be stored out of reach of children, and transferring it to other containers should be avoided as it may pose a risk of accidents and decrease in quality.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweats, pallor, severe rash with high fever, blisters, sloughing of skin, pain in mucous membranes of mouth/eyes, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with cough and fever, jaundice (yellowing of skin or eyes), severe systemic lethargy, sudden and severe headache, lightning headache, seizures, altered consciousness, visual abnormalities, paralysis, urination abnormalities

Mild side effects

• Headache
• dizziness
• abdominal pain
• indigestion
• diarrhea
• nausea
• rash
• itching
• purpura
• epistaxis

This medication should be stored in a tightly closed container to protect it from air and moisture. It is recommended to store it at room temperature between 1°C and 30°C.

Appearance

Pink round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle