Trinwon Tablets 80/5/5 mg

Adult dose

This medication should be taken once daily with water, irrespective of meals. It is recommended to take it at the same time each day (e.g., in the morning). The dose must be individualized based on the effectiveness and tolerability of Telmisartan/Amlodipine combination and Rosuvastatin for each patient. Telmisartan/Amlodipine combination can be adjusted in doses of 40/5 mg, 80/5 mg, 40/10 mg, and 80/10 mg according to blood pressure control.

This medication must not be used during pregnancy. If pregnancy is confirmed, discontinue this medication immediately, and women who may become pregnant should use appropriate contraceptive methods. This medication should not be administered to patients who are allergic to the active ingredient or other components or who have certain diseases. For example, patients with a history of angioedema, severe liver impairment, severe kidney impairment, severe aortic stenosis, or severe myopathy should not take this medication. Elderly patients, patients with hypotension, patients with hyperkalemia, and patients with poor liver function should use this medication cautiously, and periodic blood tests and physical condition checks are necessary during use. This medication may cause muscle-related adverse reactions such as myalgia or muscle weakness, and in severe cases, rhabdomyolysis; therefore, if symptoms of muscle pain or weakness occur, consult a doctor immediately. Additionally, this medication can affect liver function; thus, liver enzyme levels should be checked regularly before and during treatment, and if there is a significant increase in liver enzyme levels, discontinue use. This medication can interact with other medications; therefore, if other medications are being taken, it is essential to inform a physician or pharmacist, especially caution is needed when taken with antihypertensives, diuretics, potassium supplements, immunosuppressants, certain antibiotics, and fibrate medications. Women who are breastfeeding are advised not to take this medication, and if it is necessary to take it, breastfeeding should be discontinued. This medication is not recommended for children and adolescents under 18 years of age as its safety and efficacy have not been sufficiently established. In case of overdose, symptoms such as hypotension, dizziness, and renal function abnormalities may appear, thus seeking appropriate medical treatment immediately is necessary. While taking this medication, caution should be exercised while driving or operating hazardous machinery, as dizziness or drowsiness may occur.

Serious side effects

Angioedema, angioedema (with fatal outcomes), anaphylactic reactions, Stevens-Johnson syndrome, drug reaction with eosinophilia and systemic symptoms (DRESS), jaundice, hepatitis, liver failure, acute renal failure including kidney disorders, rhabdomyolysis, acute renal failure, thrombocytopenia, decreased urine output, kidney failure, severe edema, severe allergic reactions, severe skin adverse reactions, respiratory distress, asthma, angioedema (vascular leak syndrome)

Mild side effects

• Headache
• dizziness
• weakness
• cough
• nausea
• fatigue
• malaise
• swelling
• facial swelling
• lower limb swelling

This medication may be sensitive to light, so it should be stored in a light-protective, closed container. Furthermore, it is advisable to keep the medication at room temperature between 1°C and 30°C. Storing it this way helps maintain the medication's effectiveness and safety.

Appearance

Bright pink oval film-coated tablet

Package unit

30 tablets (10 tablets x 3)/PTP