Ezetimeb Tablet 10 mg (Ezetimibe)

Adult dosage

The recommended dosage of this medication is 10 mg once daily, taken regardless of meals. When co-administering with HMG-CoA reductase inhibitors, start the combination at the recommended initial dose of HMG-CoA reductase inhibitor, and if already receiving a high dose of HMG-CoA reductase inhibitor, continue the dose of HMG-CoA reductase inhibitor while co-administering this medication. For use with fenofibrate, in patients with mixed hyperlipidemia, this medication is co-administered with 160 mg once daily or 200 mg once daily of fenofibrate (refer to the precautions for use 4. General precautions). Administration in patients with liver impairment: No dosage adjustment is necessary for patients with mild liver impairment; however, the administration of this medication is not recommended for patients with moderate to severe liver impairment (refer to precautions for use 2. Use with caution in the following patients). Administration in patients with renal impairment: No dosage adjustment is necessary for patients with renal impairment. Administration in elderly patients: No dosage adjustment is necessary when administering to elderly patients.

This medication should not be used in patients who are allergic to specific components. Patients with active liver disease or consistently elevated liver enzyme levels should not take this medication in conjunction with specific lipid-lowering agents. Pregnant or breastfeeding women should exercise caution as the concomitant use of this medication with specific lipid-lowering agents is prohibited. Patients with moderate to severe liver function impairment may have increased exposure to this medication, leading to unexpected side effects, and therefore should avoid its use. This medication is generally well tolerated, but side effects such as headache, abdominal pain, diarrhea, fatigue, and muscle pain may occur; any unusual symptoms should prompt consultation with a physician. If muscle pain, weakness, or discomfort occurs, immediate notification to healthcare professionals is necessary and discontinuation of the medication may be warranted in severe cases. Regular liver function tests are required, and if liver enzyme levels increase, it may be necessary to adjust the treatment plan. Patients with severely impaired kidney function also require caution, particularly with concurrent use of statins, requiring dosage adjustment and monitoring. This medication may interact with other drugs, so it is essential to inform healthcare providers of any other medications being taken. Pregnant or breastfeeding women must consult a physician before taking this medication, carefully considering potential risks and benefits. It is not recommended for children under 6 years of age, and for those aged 6 and older, it should be administered according to a doctor's instructions. Elderly patients may respond sensitively to this medication and should exercise caution. In case of overdose, there is no specific antidote, and treatment will be symptomatic. This medication should be stored out of the reach of children, and it is safe not to transfer it to other containers.

Serious side effects

Hives, angioedema, anaphylaxis, hepatitis, thrombocytopenia, pancreatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis (Lyell syndrome), dyspnea, jaundice of skin or eyes, drug-induced liver injury, severe allergic reactions, severe skin adverse reactions, severe cutaneous adverse reactions (SCARs), drug reaction with eosinophilia and systemic symptoms (DRESS), rhabdomyolysis, myopathy, severe swelling or

Mild side effects

• Fatigue
• abdominal pain
• diarrhea
• viral infections
• pharyngitis
• sinusitis
• joint pain
• lower back pain
• cough
• dizziness

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is advisable to maintain a temperature between 1 and 30 degrees Celsius to preserve the medication's efficacy.

Appearance

White to off-white rectangular tablet

Package unit

10 tablets/PTP, 100 tablets/bottle, 30 tablets (10 tablets/PTP x 3)