Ciprofuzin 10/160 mg (Amlodipine Besilate, Valsartan)

Adult dose

The recommended dose is 1 tablet once daily, to be taken with water regardless of meal times. It is recommended to take it at the same time every day (e.g., in the morning). For patients with mild to moderate renal impairment, dose adjustment is usually not required; however, it should not be administered to patients with severe renal impairment, and the daily dose of Valsartan should not exceed 80 mg in patients with liver impairment. For elderly patients aged 65 years or older, careful monitoring is advised when increasing the dose.

Child dose

Safety and efficacy in pediatric patients under 18 years of age have not been established, thus administration of this medication is not recommended.

This medication can cause significant harm to the fetus and newborn if taken during the second and third trimesters of pregnancy, so it should be discontinued immediately upon confirmation of pregnancy. It is safe not to take this medication if there is an allergy to its active ingredients or similar class medications, if the person is pregnant or breastfeeding, or if there are serious kidney or liver diseases. Patients with sodium or fluid depletion may experience hypotension, so their condition should be well monitored before taking this medication, and blood pressure and symptoms should be carefully observed during treatment. Patients with high potassium levels should be cautious when taking this medication with other drugs that can increase potassium and should undergo regular potassium level testing. Patients with renal vascular issues or those who have received kidney transplants need strict monitoring by healthcare professionals as kidney function may worsen. If swelling in the face or neck area, known as angioedema, occurs, discontinuation of the drug should be immediate and consultation with healthcare professionals is required; re-administration may be dangerous. Patients with heart failure or post-myocardial infarction should carefully monitor kidney function and blood pressure changes while taking this medication, and those with acute myocardial infarction need to be cautious as well. Patients with aortic stenosis or obstructive hypertrophic cardiomyopathy should be particularly careful when taking this medication. The risk of side effects may increase when this medication is used in conjunction with other blood pressure medications, so drug interactions should be confirmed in consultation with a healthcare provider. Dizziness or fatigue may occur when driving or operating machinery, so caution is advised. In case of overdose, serious hypotension or heart-related side effects may occur, hence it is important to adhere strictly to the recommended dosage and inform healthcare professionals immediately if any abnormal symptoms arise.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormality accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme fatigue, sudden and severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination

Mild side effects

• Headache
• dizziness
• drowsiness
• paresthesia
• vertigo
• tinnitus
• tachycardia
• palpitations
• orthostatic hypotension
• hypotension

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture, and it is recommended to store it at a temperature between 1 to 30 degrees Celsius.

Appearance

Bright yellow, oval-shaped film-coated tablet

Package unit

28 tablets/box[14 tablets/PTPX2], 30 tablets/bottle, 100 tablets/bottle