Inihial Plus Injection (Pre-filled) (Sodium Hyaluronate)

Adult dosage

Typically, 1 vial is administered once a week for 3 consecutive weeks into the knee joint or the shoulder joint (subacromial bursa or bicipital tendon sheath), but the number of injections may be adjusted according to the symptoms.

This medication should not be used in patients who have had allergic reactions to any component of this product. Caution is advised for patients with allergies to other medications or those with liver function impairment or a history of liver disorders. Careful examination should be conducted before using this product if there is a skin disease or infection at the injection site. Severe allergic reactions such as shock may occur when using this medication, so careful observation is necessary, and immediate cessation and appropriate treatment should be sought if any unusual symptoms arise. Allergic symptoms such as swelling or redness around the face or eyes, rash, hives, or itching may occur, and if these symptoms arise, use should be discontinued immediately. Pain, swelling, redness, warmth, or discomfort may appear at the injection site, and infusion of fluid into the joint may occur rarely, so attention is required regarding these symptoms. Nausea, vomiting, fever, and other symptoms may occur occasionally. Injecting this medication into joints with severe inflammation may worsen the inflammation, so it is advisable to alleviate the inflammation first before use. Stabilizing the injection site after administering the medication is helpful, and it is important to ensure that the drug does not leak outside the joint. As this medication is injected into the joint, strict aseptic techniques must be maintained during administration, and if symptoms do not improve, it should only be administered up to three times and then discontinued. If fluid accumulates within the joint, it should be aspirated as necessary. Intravenous injection is strictly prohibited, and this product is not suitable for ophthalmic use. A syringe needle of gauge 22-23 is recommended for administration. This medication may react with certain disinfectants, resulting in precipitation, so caution is required not to use it alongside disinfectants such as benzalkonium chloride or chlorhexidine. Women who are pregnant or may become pregnant should use this medication cautiously only if the benefits of treatment outweigh the risks. Also, as this drug can be passed through breast milk, it is advisable to avoid breastfeeding while using this medication. Caution is necessary when using this product in children, as safety has not been adequately established, and it should only be used cautiously when absolutely necessary. Elderly patients may have decreased bodily functions and should be particularly cautious when using this medication.

Serious side effects

Hives, swelling, shock symptoms (severe allergic reactions)

Mild side effects

• Swelling (facial, eyelid, etc.)
• facial flushing
• rash
• itching
• pain (transient)
• edema
• redness
• warmth
• local tenderness
• nausea

This medication should be stored in a sealed container to prevent exposure to air and moisture, and it is recommended to be kept at room temperature between 1 degree and 30 degrees Celsius. Storing this way helps maintain the effectiveness of the medication.

Appearance

A colorless, transparent, and viscous liquid contained in a glass or plastic tube sealed at both ends with rubber stoppers (part of the pre-filled syringe system).

Package unit

2mL x 1 vial, 2mL x 3 vials