Linagliptin Metformin Tablets 2.5/1000 mg

Adult dose

The dosage of this medication is determined based on the maximum recommended doses of each component, which are 2.5 mg of linagliptin and 1000 mg of metformin, not exceeding twice daily, considering the patient's current treatment regimen, efficacy, and tolerability. This medication is to be taken twice daily with meals. 1. If the patient is not currently being treated with metformin: the initial dose is this medication 2.5/500 mg, taken twice daily, 1 tablet per dose.

This medication is used to treat type 2 diabetes and helps to control blood glucose levels. This medication may cause serious side effects such as lactic acidosis, so it should not be used in patients with poor kidney function, heart disease, or liver dysfunction. In particular, patients with an allergy to any of the components included in this medication or those with type 1 diabetes, pregnant or breastfeeding women should not take it. Due to the risk of hypoglycemia, caution is required when using this medication with insulin or sulfonylureas, and doses of other medications may be adjusted as necessary. If kidney function is impaired, it is essential to check kidney function before using this medicine and monitor it regularly. This medication should be temporarily discontinued during surgery or radiological examinations, and it can be restarted after kidney function has recovered. Skin conditions like acute pancreatitis or bullous pemphigoid may occur, and any abdominal pain or skin abnormalities during use should be reported to a doctor immediately. Gastrointestinal disturbances such as diarrhea, abdominal pain, nausea, and vomiting may occur during the use of this medication, but most improve naturally over time. As vitamin B12 levels may decrease, regular blood tests are recommended during long-term use to check levels. This medication may interact with other drugs, so inform your doctor or pharmacist of any other medications you are taking. Women who are pregnant or planning to become pregnant should avoid taking this medication and use other treatments for blood glucose control. Elderly patients should have their kidney function checked frequently, as decreased kidney function is common, and it is advisable to start with the lowest dose. It is recommended not to use this medication in children under 10 years of age, as safety and efficacy have not been established. In case of overdose, serious side effects such as lactic acidosis may occur, so the dosage must be strictly adhered to, and if any unusual symptoms appear, immediate medical attention should be sought. This medication should be stored in a cool, dry place away from moisture and direct sunlight, out of reach of children.

Serious side effects

Urticaria, angioedema, lactic acidosis, pancreatitis, bullous pemphigoid, chest tightness, difficulty breathing, asthma attack, yellowing of skin or eyes (jaundice), liver dysfunction, sudden and severe headache, seizures, confusion, visual disturbances, paralysis, significant decrease in urine output, severe swelling of the body and hypertension, angina pectoris, acute myocardial infarction, unstable angina, cardiac arrest, congestive heart failure, heart failure, acute

Mild side effects

• Nasopharyngitis
• hypersensitivity
• vitamin B12 deficiency and depletion
• hypoglycemia
• taste disorder
• cough
• decreased appetite
• diarrhea
• constipation
• nausea

This medication is sensitive to air and moisture and should be stored in a tightly closed container. The recommended storage temperature is between 1 to 30 degrees Celsius. Proper storage will help maintain the effectiveness of the medication.

Appearance

Light pink, double-convex, oval film-coated tablet

Package unit

60 tablets (10 tablets/PTP packaging x 6 units)