Nexocan Tablet 20 mg (Esomeprazole Magnesium Hemihydrate)

Adult dosage

This medication should be swallowed with liquid such as water and should not be chewed or crushed. 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: administer 40 mg once daily for 4 weeks. If not resolved or symptoms persist, an additional 4-week treatment may be required. - Maintenance therapy for the prevention of esophagitis recurrence: 20 mg once daily. - Treatment of gastroesophageal reflux disease symptoms without esophagitis:

Children's dosage

Adolescents 12 years and older - Treatment of erosive reflux esophagitis: administer 40 mg once daily for 4 weeks. If not resolved or symptoms persist, additional 4-week treatment may be required. - Treatment of gastroesophageal reflux disease without esophagitis symptoms:

This medication should not be used in patients with known allergies or hypersensitivity to any of its components. Additionally, caution is required when used in conjunction with penicillin or macrolide antibiotics in patients with allergies to these medications. Women who are breastfeeding or patients with a history of myocardial infarction should avoid using this medication. This product contains certain colorants, and should be used with caution in individuals allergic to them. During treatment, rare side effects may occur, including blood cell count decreases, allergic reactions, insomnia, headache, abdominal pain, and more. Long-term use may result in electrolyte imbalances, such as low magnesium levels, necessitating regular check-ups. As this medication suppresses gastric acid secretion, it may increase the risk of certain bacterial infections, so patients should consult a doctor if diarrhea persists. Special caution is needed for patients at risk of osteoporosis, as long-term use may increase the risk of fractures. Drug interactions may occur, so it is imperative that patients inform their healthcare providers of any medications they are taking. The safety of this medication during pregnancy has not been conclusively established, so pregnant women should consult with a doctor before use. In case of overdose, as there is no specific antidote, appropriate treatment should be administered based on the symptoms, and it should be stored out of reach of children.

Serious side effects

• Urticaria, angioedema → severe allergic reaction
• Fever (high fever may indicate severity)
• Skin peeling, mucosal pain in the mouth/eyes, erythema multiforme, mucocutaneous syndrome (Stevens-Johnson syndrome), toxic epidermal necrolysis (Lyell syndrome), acute generalized exanthematous pustulosis, eosinophilia with systemic symptoms (DRESS syndrome) → severe skin reactions
• Difficulty breathing, dyspnea, exacerbation of asthma, bronchospasm, post-operative

Mild side effects

• Blood and lymphatic system: leukopenia, thrombocytopenia, agranulocytosis, pancytopenia
• Immune system: fever, angioedema, hypersensitivity reaction
• Metabolism/nutrition: peripheral edema, hyponatremia, hypomagnesemia
• Psychiatric: insomnia, agitation, confusion, depression, aggression, hallucinations
• Nervous system: headache, dizziness, paresthesia, drowsiness, taste disorder
• Vision: blurred vision
• Auditory and vestibular system: dizziness
• Respiratory system: bronchospasm
• Gastrointestinal:

This medication may be sensitive to air or moisture; therefore, it should be stored in a tightly sealed container. It is best stored at room temperature between 1°C and 30°C. This way, the efficacy of the medication can be maintained over a longer period.

Appearance

Light pink oval film-coated tablet

Package unit

28 tablets (14 tablets/Alu-Alu * 2)