Neurodon Tablets 10 Milligrams (Donepezil Hydrochloride Trihydrate)

Adult dose

○ Adults: Administer 5 mg of donepezil hydrochloride once daily at bedtime. If sleep disturbances such as unusual dreams, nightmares, or insomnia occur, morning administration of this medicine may be considered. Since donepezil reaches steady state 15 days after administration and the frequency of adverse reactions may be affected by the rate of dose escalation, administer the 5 mg dose for 4~6 weeks. After evaluating the clinical response during this period, the dose may be increased to 10 mg. When increasing the dose to 10 mg once daily, administer with caution for gastrointestinal adverse reactions. If this medicine is discontinued, its effects gradually diminish, and no rebound effect occurs following abrupt discontinuation. ○ Women weighing less than average and aged 85 years or older: Careful monitoring is necessary because adverse reactions occur more frequently. Elderly women with low body weight should not exceed 5 mg per day.

Child dose

○ Children: There is no experience with use in children.

This medication contains the ingredient donepezil hydrochloride and is mainly used for alleviating symptoms in patients with Alzheimer's-type dementia. First, this medication should not be administered to certain patients. For example, individuals who are allergic to this drug or its components, pregnant women or women who may become pregnant, as well as patients with a genetic lactose intolerance issue should not take it. Next, patients with heart disease or history of gastric ulcers, asthma or pulmonary disease, patients with extrapyramidal disorders such as Parkinson's disease, and individuals allergic to specific colorants included in this medication should take it cautiously. While taking this medication, various side effects may occur. Cardiac-related problems can include bradycardia, heart block, and myocardial infarction. Digestive tract issues may present as gastric ulcers or gastrointestinal bleeding, vomiting, diarrhea, and others. The nervous system may experience seizures, hallucinations, insomnia, and dizziness, while muscle pain or movement disorders may also arise. In particular, this medication can affect cardiac conduction, so patients with heart disease or a history of QT interval prolongation should regularly monitor their condition through electrocardiograms. Moreover, this medication may interact with other drugs, therefore if you are currently on other medications, it is essential to consult with a doctor or pharmacist. Exercise caution when taken alongside antibiotics, antidepressants, antiarrhythmics, and some pain relievers. Pregnant or breastfeeding women should preferably avoid this medication. If necessary, it is recommended to consult a professional and consider ceasing breastfeeding. There is insufficient data to guarantee the safety of this medication in children; thus, it should not be administered to pediatric patients. In cases of overdose, serious symptoms such as vomiting, bradycardia, and respiratory depression may occur, requiring immediate medical attention for appropriate treatment. Finally, this medication should be stored out of reach of children and should not be transferred to another container for safety.

Syncope, bradycardia, heart block, QT interval prolongation, myocardial infarction, heart failure, peptic ulcer, perforated duodenal perforation, gastrointestinal bleeding, hepatitis, liver dysfunction, jaundice, cerebral seizure, cerebral hemorrhage, cerebrovascular disorder, motor dysfunction, ataxia, movement disorder, dystonia, tremors, involuntary movement, gait disorder, abnormal posture, speech disorder, akinetic mutism, extreme muscle rigidity, dysphagia, tachycardia, blood pressure fluctuations, sweating, myalgia, weakness, dyspnea, acute pancreatitis, acute renal failure, sudden death, cold, anorexia, hallucinations, agitation, aggressive behavior, anxiety disorder, insomnia, drowsiness, increased libido, talkativeness, mania, nightmares, nervousness, nonsensical speech, delusions, depression, confusion, apathy, hyperactivity, hypersexuality, dizziness, tremors, seizures, stupor, pleuritic chest pain, palpitations, sinoatrial block, atrioventricular block, hypertension, hypotension, atrial fibrillation, torsades de pointes, electrocardiogram QT interval prolongation, diarrhea, nausea, vomiting, abdominal disorder, gastro-duodenal ulcer, constipation, salivation, fecal incontinence, liver disorder, rash, itching, urinary incontinence, polyuria, urinary retention, headache, fatigue, pain, toothache, facial flushing, lethargy, asthenia, edema, fever, decreased body temperature, decreased hematocrit, leukopenia, anemia, thrombocytopenia, petechiae, abnormal dreams, decreased appetite, urinary tract infection, increased CPK, dehydration, hyperlipidemia, insomnia, hostility, irritability, drowsiness, depression, confusion, emotional instability, personality disorder, eczema, urinary incontinence, abdominal pain, weakness, fungal infection, influenza-like syndrome, allergy, soft tissue infection, lethargy, sepsis, facial edema, hernia, hypotension, ECG abnormalities, heart failure, myocardial infarction, angina, atrial fibrillation, congestive heart failure, peripheral vascular disease, supraventricular ectopic beats, ventricular ectopic beats, cardiac hypertrophy, constipation, gastroenteritis, fecal incontinence, dyspepsia, increased γ-GT, gastritis, dysphagia, periodontitis, gastric ulcer, periodontal abscess, abdominal bloating, liver dysfunction, belching, esophagitis, anal bleeding, diabetes, anemia, leukocytosis, weight loss, peripheral edema, edema, increased LDH, increased alkaline phosphatase, hypercholesterolemia, hypokalemia, hypoglycemia, weight gain, hyperbilirubinemia, increased BUN, B12 deficiency anemia, cachexia, increased creatinine, gout, hyponatremia, hypoproteinemia, iron deficiency anemia, increased AST, increased ALT, arthritis, arthrosis, bone fracture, arthralgia, leg cramps, osteoporosis, myalgia, anxiety, nervousness, seizures, transient psychosis, gait abnormalities, apathy, delusions, abnormal dreams, cerebrovascular abnormalities, increased salivation, ataxia, euphoria, vasodilation, cerebral hemorrhage, cerebral infarction, cerebral ischemia, dementia, extrapyramidal symptoms, grand mal seizures, hemiplegia, hypertonia, decreased movement, pharyngitis, pneumonia, increased cough, bronchitis, dyspnea, rhinitis, asthma, rash, skin ulcer, itching, psoriasis, skin discoloration, shingles, dry skin, sweating, urticaria, vesicular rash, conjunctivitis, glaucoma, visual disturbances, ear pain, tear abnormalities, urinary tract infection, cystitis, hematuria, diabetes, vaginitis, urination disorders, polyuria, proteinuria, abdominal pain, anxiety, cholecystitis, confusion, seizures, hallucinations, heart block, hemolytic anemia, hyponatremia, neuroleptic malignant syndrome, pancreatitis, rash

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture. It is recommended to maintain a storage temperature between 1 and 30 degrees Celsius. Proper storage helps to preserve the medication's effectiveness and prevent deterioration.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle