Pioformin Tablets 15/850 Milligrams

Adult dosage

The dosage of this medication should be individualized based on efficacy and tolerability, not exceeding the maximum doses of pioglitazone 30mg and metformin 2500mg. The initial dose should be based on the patient's current therapy. Start with one tablet once daily and gradually adjust the dosage while evaluating the appropriateness of the therapeutic response. This medication is generally administered divided with meals to reduce gastrointestinal side effects caused by metformin.

This medication can cause severe lactic acidosis and hypoglycemia, so if such symptoms occur, you should immediately stop taking it and consult a doctor. Lactic acidosis is a rare but very serious condition, and the risk increases in cases of poor kidney function or conditions such as heart disease or infection. Patients with impaired liver function should avoid using this medication, and excessive alcohol consumption should also be avoided. In patients with heart failure, this medication may worsen symptoms, so any signs of heart failure should be reported to a doctor immediately. This medication should not be used in patients with severe renal impairment, active bladder cancer, or type 1 diabetes. Additionally, its administration should be temporarily suspended in cases of preoperative, postoperative, acute infections, or dehydration. While taking this medication, regular monitoring of blood glucose levels, kidney function, liver function, and hematological tests should be conducted, and particularly elderly patients should be more cautious. This medication may interact with other drugs, so if you are taking any other medications, you must inform your doctor or pharmacist. Pregnant or breastfeeding women should not take this medication, and premenopausal women should consider the possibility of pregnancy during the use of this medication and employ appropriate contraception. In case of overdose, you should immediately visit a medical institution for appropriate treatment, as some components may be removed by blood dialysis. While taking this medication, it is important to be attentive to any changes in symptoms, and if any adverse symptoms occur, immediate consultation with healthcare professionals is essential.

Serious side effects

Severe lactic acidosis, hypoglycemia, acute renal function deterioration, worsening of cardiopulmonary disease, sepsis, deaths due to lactic acidosis, severe allergic reactions (hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor), severe skin adverse reactions (severe rash with fever, blisters, skin peeling, pain in the mucous membranes of the mouth/eyes), respiratory problems (shortness of breath or difficulty breathing, asthma attacks, respiratory distress accompanied by cough + fever)

Mild side effects

• Upper respiratory infection
• diarrhea
• nausea
• headache
• urinary tract infection
• sinusitis
• dizziness
• lower extremity edema
• weight gain
• myalgia

This medication should be stored in a tightly closed container to prevent exposure to air or moisture, ideally at room temperature between 1 to 30 degrees Celsius. This storage method will help maintain the effectiveness of the medication for a longer period.

Appearance

White to grayish-white, rectangular film-coated tablet

Package unit

30 tablets (10 tablets/PTP * 3)