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Metformin Hydrochloride 500mg · Glimepiride 2mg
Tablet · Prescription medication · Combination
Seongwon Adcock Pharmaceutical Co., Ltd.

MFDS item code 201801420 · Approved 2018.03.30 · Insurance code 664901570
Improvement of blood glucose control in type 2 diabetes
This medication assists in controlling blood glucose levels in patients with type 2 diabetes, serving as an adjunct to diet and exercise. Glimepiride and metformin work together to effectively lower blood glucose levels, making it suitable for those who require blood glucose management.
This medication is administered 1-2 times a day, before or with meals. Dosages may be adjusted based on each patient's current treatment regimen, efficacy, and tolerance, with appropriate blood glucose monitoring required. Treatment typically starts at a low dose, and dosage can be adjusted considering the drugs currently taken by the patient and their blood glucose levels. In clinical trials, the initial daily dosage was Glimepiride / Metformin Hydrochloride.
This medication may cause severe lactic acidosis or hypoglycemia; therefore, caution is needed. In particular, if kidney function deteriorates rapidly, metformin may accumulate in the body and increase the risk of lactic acidosis, so patients with poor kidney function should avoid taking it. In cases of dehydration, severe diarrhea, vomiting, or fever, the use of this medication should be temporarily discontinued, and a doctor must be consulted. Additionally, certain medications may affect kidney function when used concurrently, so healthcare providers should be informed of any other medications being taken. Patients at risk for cardiovascular disease should be particularly cautious as this medication may increase cardiovascular mortality. This medication should not be administered to patients with insulin-dependent diabetes, acute metabolic acidosis, severe liver dysfunction, severe kidney impairment, or to pregnant or nursing women. During treatment, there is a risk of hypoglycemia, so patients should avoid skipping meals, excessive exercise, and alcohol consumption, and should frequently monitor their blood glucose levels. Gastrointestinal side effects such as diarrhea, nausea, and vomiting may occur, so it is helpful to take this medication with food initially. In case of allergic reactions, it is important to inform the physician immediately and stop taking the medication. This medication may reduce vitamin B12 levels, so regular monitoring of vitamin B12 status is advisable for long-term users. Blood glucose control should be regularly checked, and kidney function should also be periodically evaluated, as dosage adjustments may be necessary depending on the condition. Overdosage may lead to hypoglycemia or lactic acidosis, so immediate medical attention should be sought for appropriate treatment. If pregnant or planning to become pregnant, or if breastfeeding, this medication should not be used, and appropriate treatment methods should be discussed with a doctor. Care should be taken when driving or operating machinery as hypoglycemia or dizziness may increase the risk of accidents. When storing this medication, keep it out of reach of children and avoid transferring it to other containers.
Urticaria, severe swelling (edema), chest tightness, difficulty breathing, hypotension, shock, cardiac arrest → severe allergic reaction; high fever accompanied by severe rash, blisters, skin peeling, oral/ocular mucosal pain → severe skin adverse reaction; shortness of breath or difficulty breathing, asthma attacks, coughing with fever → respiratory problems; skin or eyes turning yellow (jaundice), extreme lethargy → liver problems (jaundice)
Abdominal pain, abdominal distension, loss of appetite, dyspepsia, constipation, diarrhea, nausea, vomiting, upper abdominal fullness or pressure, altered taste, metallic taste, visual impairment related to blood glucose changes, erythema, itching, rash, urticaria, facial swelling, erectile dysfunction, flushing, gastritis, thrombocytopenia, leukopenia, hemolytic anemia, anemia, granulocytopenia, agranulocytosis, pancytopenia, peripheral neuropathy associated with vitamin B12 deficiency,
Not everyone experiences these, and they can vary from person to person.
This medication should be stored in a tightly closed container that prevents air and moisture from entering. It is best to avoid extremes of temperature, storing it at room temperature between 1 and 30 degrees Celsius.
White oblong film-coated tablet
30 tablets/bottle, 300 tablets/bottle
Even with the same ingredient, strength, dosage form and how it is taken can differ.
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Tablet · Prescription medication · Combination
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Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.
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For anything that needs medical judgment, consult a doctor or pharmacist.
This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.