Medication info
Cardilet Tablets 5/10 mg

Cardilet Tablets 5/10 mg

Prescription medicationTablet경구
Ingredient · strength
Atorvastatin Calcium›10.36mg / 1 tabletAmlodipine Besylate›6.94mg / 1 tablet
Manufacturer / importer
(주)퍼슨
Appearance
White oval film-coated tablets
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201801331 · Approved 2018.03.27 · Insurance code 657401790

Summary

Main use
Reduces the risk of hypertension and coronary artery heart disease, improves dyslipidemia
Who takes it
Adults
Adult dose
This medication is administered only to adults, and the dosage must be individualized based on the effects and tolerance of each component, amlodipine/atorvastatin, for each patient. Amlodipine (S-Amlodipine): Administer 5 (2.5) mg orally once daily, and the dosage may be increased up to 10 (5) mg daily based on patient response. Atorvastatin: Patients with primary hypercholesterolemia and dyslipidemia should take 10 mg once daily.

Ingredients

Manufacturer
(주)퍼슨

Efficacy & effects

Reduces the risk of hypertension and coronary artery heart disease, improves dyslipidemia

  • Hypertension
  • fixed occlusion of the coronary artery
  • coronary vascular spasm
  • vasoconstriction
  • myocardial ischemia
  • angina
  • multiple risk factors for coronary artery heart disease
  • myocardial infarction
  • stroke
  • chronic stable angina
  • type 2 diabetes
  • non-fatal myocardial infarction
View approved original text

This medication is used for patients who require the combined treatment of amlodipine, which is used for the treatment of hypertension and angina, and atorvastatin, which is used to reduce high cholesterol and cardiovascular risks. Amlodipine dilates blood vessels to lower blood pressure, improves myocardial ischemia due to stable and variant angina, and reduces the risk of hospitalization for angina and the need for vascular intervention. Atorvastatin reduces the risk of myocardial infarction, stroke, vascular intervention, and angina in patients at high risk for coronary artery heart disease and stroke, and helps improve cholesterol and triglyceride levels in patients with dyslipidemia. Particularly, it reduces cardiovascular risks in high-risk groups, including diabetes patients and those with a family history. The combination of these two medications plays a vital role in effectively managing cardiovascular health, contributing to the overall reduction of cardiovascular disease risk.

How to take

Adult dose

This medication is administered only to adults, and the dosage must be individualized based on the effects and tolerance of each component, amlodipine/atorvastatin, for each patient. Amlodipine (S-Amlodipine): Administer 5 (2.5) mg orally once daily, and the dosage may be increased up to 10 (5) mg daily based on patient response. Atorvastatin: Patients with primary hypercholesterolemia and dyslipidemia should take 10 mg once daily.

Precautions

This medication should not be used in certain patients. For example, it should not be taken by those who are allergic to this drug or similar components, those with severe liver problems or active liver diseases. Women who are pregnant or may become pregnant, nursing mothers, patients with muscle disorders, severe aortic stenosis, patients in shock, those within one month post-myocardial infarction, patients with unstable angina, and those taking certain antiviral medications should also avoid this drug. This medication should be used with caution in patients with severely impaired kidney function, elderly patients, alcoholics or those with a history of liver disease, patients at risk for muscle disorders, acute heart failure, patients with very high blood pressure or weakened liver function, and those with severe myasthenia. While taking this drug, side effects such as fatigue, edema, dizziness, headaches, dyspepsia, and myalgia may occur, and rarely hepatic dysfunction or allergic reactions can also happen. Regular liver function tests and muscle-related tests should be conducted, and immediate medical advice should be sought if muscle pain or weakness occurs. Women who are pregnant or nursing should not use this drug, and women who may become pregnant should take appropriate contraceptive measures. Additionally, this drug's safety in children or elderly patients has not been sufficiently established, so caution is required. In cases of overdose, blood pressure may drop too low or heart function may be compromised, so immediate contact with medical personnel is necessary, and emergency treatment should be received if needed. This drug may interact with other medications, so if there are any currently taken medications, it is essential to inform the doctor or pharmacist, especially when taken with certain antibiotics, antifungals, antivirals, blood pressure drugs, and anticoagulants.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, skin peeling, pain in oral/eye mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough + fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headache, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

  • Flushing
  • fatigue
  • edema
  • palpitations
  • dizziness
  • headaches
  • drowsiness
  • abdominal pain
  • nausea
  • weakness
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  • lethargy
  • pain
  • weight gain or loss
  • hypotension
  • vasculitis
  • muscle tension
  • sensory loss
  • paresthesia
  • peripheral neuropathy
  • syncope
  • dysgeusia
  • tremors
  • extrapyramidal disorders
  • erectile dysfunction
  • gynecomastia
  • changes in bowel habits
  • dry mouth
  • dyspepsia
  • gingival hypertrophy
  • gum hyperplasia
  • pancreatitis
  • vomiting
  • hyperglycemia
  • arthralgia
  • back pain

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. Additionally, it should be stored at room temperature between 1 and 30 degrees Celsius. Storing it this way helps to maintain the medication's efficacy for a longer period.

Appearance and packaging

Appearance

White oval film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.