Bielglime Tablet 2 mg (Glymepiride)

Adult dose

Individual adjustment is required for each patient. This medication is taken orally once daily and should be taken before breakfast or right before the first meal. It needs to be swallowed without chewing, with at least a half-cup of water. For monotherapy, the initial dose is 1 mg of glymepiride taken orally once daily, and dosage may be increased by 1 mg at intervals of 1 to 2 weeks. Generally, there is little additional effect when administering more than 4 mg.

This medication should not be used in patients with insulin-dependent diabetes, diabetic ketoacidosis, or in a coma. Additionally, patients who have had hypersensitivity reactions to this medication, its components, sulfonylureas, or sulfonamide medications should not take this product. In cases of severe liver or kidney dysfunction, switching to insulin treatment is recommended instead of using this medication. Pregnant women, women who may become pregnant, and breastfeeding women should also avoid taking this medication. Patients with severe infections, undergoing surgery, or in a state of serious trauma should receive insulin treatment instead of this medication. Patients with gastrointestinal disturbances such as diarrhea or vomiting should be cautious, as these can lead to problems with food absorption and increase the risk of hypoglycemia. This medication contains lactose, so patients with galactose intolerance, lactase deficiency, or glucose-galactose malabsorption should not take it. During the first week of dosing, the risk of hypoglycemia is higher, so careful monitoring of blood sugar levels is essential. Patients with poor nutritional status, irregular meal patterns, or imbalances in physical activity and carbohydrate intake are at greater risk for hypoglycemia. Caution is also advised for patients who consume alcohol, have decreased kidney and liver function, elderly patients, and those with certain endocrine disorders, as they may have an increased risk of hypoglycemia. When taking this medication with other drugs, interactions may occur; therefore, it is crucial to inform your doctor or pharmacist about any other medications being taken. This medication contains Yellow No. 4 (Tartrazine) and should be used with caution in patients allergic to this component. Hypoglycemic symptoms may arise while taking this medication, so if symptoms such as headache, severe hunger, nausea, fatigue, confusion, drowsiness, or loss of consciousness occur, it is crucial to consume sugar immediately and inform medical staff. Temporary blurred vision or visual disturbances may occur, and gastrointestinal symptoms such as nausea, vomiting, abdominal pain, and diarrhea may develop. Liver dysfunction or blood-related adverse reactions may rarely occur, so immediate consultation with medical personnel is necessary if unusual symptoms arise. Allergic reactions such as itching, rash, or difficulty breathing may occur, and in severe cases may progress to shock, so caution is needed. This medication must be taken regularly, and optimal blood sugar control requires adherence to dietary and exercise therapy. In case of hypoglycemia, it is important to rapidly ingest foods or beverages containing sugar, as artificial sweeteners do not help control hypoglycemia. Pregnant or breastfeeding women should not take this medication and should switch to insulin treatment for safety. The safety and efficacy of this medication have not been established in pediatric patients under 18 years of age, thus it should not be used in this population. In cases of overdose, severe hypoglycemia may occur, necessitating immediate medical care.

Serious side effects

Hives, severe swelling (angioedema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reaction, severe rash with fever, blisters, peeling skin, pain of mucous membranes in the mouth/eyes, severe skin reactions, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities with coughing and fever, liver abnormalities (jaundice), sudden and severe headache, lightning-like headaches, seizures, confusion, visual disturbances, paralysis.

Mild side effects

• Headache
• severe hunger
• nausea
• vomiting
• fatigue
• sleep disturbance
• anxiety
• aggression
• reduced concentration
• decreased dexterity or activity

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is important to maintain storage temperatures between 1°C to 30°C to preserve the medication's efficacy and safety for an extended period.

Appearance

Green rectangular tablet

Package unit

30 tablets/bottle, 300 tablets/bottle