International Pioglitazone Tablet 30 mg (Pioglitazone Hydrochloride)

Adult dose

This medication should be taken orally once a day regardless of meals. 1. Monotherapy It can be initiated at a dose of 15 mg once daily, and if efficacy is insufficient, it can be titrated up to 30 mg once daily. 2. Combination therapy When used in conjunction with sulfonylureas, metformin, or insulin, the initial dose is 15 mg once daily. The maximum recommended dose does not exceed 30 mg once daily.

Child dose

There is no experience with use in children under 18 years of age, so administration is not recommended.

This medication is used for the treatment of type 2 diabetes and helps improve insulin resistance to control blood sugar. During the course of treatment with this medication, it may place a burden on the heart, so it should not be given to patients with congestive heart failure or a history of heart failure. Symptoms of heart failure such as weight changes, shortness of breath, and swelling should be closely monitored after starting treatment or increasing the dose, and if any symptoms appear, immediate consultation with a healthcare professional is necessary. This medication can cause fluid retention, worsening heart failure, so it should be used cautiously in patients with heart disease or those at high risk of fluid retention. Patients with active bladder cancer or a history of bladder cancer should not receive this medication, and if symptoms of hematuria or urinary disorders occur during treatment, they should be reported to a doctor immediately. Patients with impaired liver function, severe kidney disease, or diabetic ketoacidosis should avoid using this medication. Caution is needed when used in conjunction with other oral hypoglycemic agents as the risk of hypoglycemia may increase, particularly when used alongside sulfonylureas or insulin, and symptoms of hypoglycemia should be carefully observed. Common side effects may include swelling, headache, upper respiratory infections, muscle pain, pharyngitis, abdominal bloating, weight gain, urinary tract infection, hypoglycemia, back pain, dizziness, diarrhea, elevated creatine kinase, hypertension, itching, chest pain, fatigue, weakness, indigestion, nausea, chest discomfort, tremors, chills, gastrointestinal disorders, discomfort in the epigastric region, numbness, muscle stiffness, discomfort in the head, increased liver enzymes, hives, eczema, joint pain, knee problems, arm weakness, and protein in urine. This medication may cause weight gain, so regular monitoring of weight changes during treatment is important. It is advisable not to use this medication in pregnant women or women who may become pregnant, and premenopausal women should utilize appropriate contraception while taking this medication as it may induce ovulation. Elderly patients or those with decreased kidney or liver function require more careful monitoring during treatment with this medication. This medication is taken once daily, and care should be taken not to double the dose if a dose is missed on the following day. There may be drug interactions, so if other medications are being taken, it is essential to inform the doctor or pharmacist. During treatment with this medication, regular blood glucose and liver function tests should be conducted to monitor therapeutic effect and side effects. In case of overdose, even without specific symptoms, it is important to visit a medical institution immediately for appropriate treatment. Keep out of reach of children and store the medication in its original container.

Serious side effects

Severe swelling (edema), difficulty breathing, congestive heart failure, heart failure, liver abnormalities (jaundice), severe neurological symptoms (stroke, myocardial infarction), elevated blood pressure, heart failure, severe allergic reactions (hives), bladder cancer, severe skin reactions (including hives), severe hypoglycemia, and severe swelling or urinary abnormalities (visible hematuria, urinary disorders, urinary urgency)

Mild side effects

• Headache
• upper respiratory infection
• sinusitis
• muscle pain
• pharyngitis
• abdominal bloating
• weight gain
• urinary tract infection
• hypoglycemia
• back pain

This medication should be stored in a container that does not allow light and air to penetrate and should be kept away from humid areas. Additionally, to maintain the efficacy of the medication, it is recommended to store it in a cool place at a temperature between 15 and 30 degrees Celsius, preferably around 25 degrees.

Appearance

White round tablet

Package unit

30 tablets/bottle, 100 tablets/bottle