Amlomin Tablet 5 mg (Amlodipine Besilate)

Adult dosage

Administer 5 mg orally once a day as amlodipine, and the dose may be increased to a maximum of 10 mg per day based on patient response. Adjust according to age and symptoms.

This medication should not be administered to certain patients. For instance, it is not to be used in individuals with allergies to this medication or similar types of drugs, women who are pregnant or may become pregnant, women who are breastfeeding, patients with severe liver dysfunction, patients with severe aortic stenosis, and those in shock. In addition, this medication must be used with caution. Special attention is required in patients with severe hypotension, those who require dialysis due to renal failure, and in elderly individuals. Various side effects may occur while taking this medication. The most common side effects include flushing or symptoms of vasodilation, fatigue, swelling, palpitations, dizziness, headache, drowsiness, abdominal pain, and nausea. Rarely, severe hypotension, vasculitis, neurological symptoms, erectile dysfunction, gynecomastia, dyspepsia, weight changes, skin rashes, hair loss, liver function abnormalities have been reported, and in severe cases, allergic reactions or cardiac issues may occur. Patients with heart failure or impaired liver function should use this medication with greater caution, and if blood pressure drops too low, the effects may continue even after discontinuation of the medication; thus, careful monitoring of doses and administration intervals when used with other antihypertensives is necessary. This medication is not suitable for emergency treatment as its effects may take time to manifest in acute unstable angina. It is reported that this medication does not significantly affect the ability to drive or operate machinery. This medication may interact with other drugs; therefore, it is essential to inform healthcare professionals of any medications being taken simultaneously. In particular, concomitant use with grapefruit juice should be avoided as it may increase blood pressure-lowering effects. The safety of this medication has not been established in pregnant or breastfeeding women; thus, it is advisable to avoid use in special cases, and breastfeeding should be discontinued during its use. Safety and efficacy in children have not been adequately confirmed. In the elderly, it is recommended to use the standard dosage, as tolerance is similar to that of younger patients. In cases of overdose, severe hypotension and tachycardia may occur, necessitating close monitoring of cardiac and respiratory functions and appropriate emergency measures. Hemodialysis may not be effective, therefore other treatments should be utilized. No reports of carcinogenicity or mutagenicity have been associated with prolonged use of this medication.

Serious side effects

• Urticaria
• severe swelling (edema)
• skin peeling
• pain in oral/ocular mucosa
• difficulty breathing
• asthma attacks
• visual disturbances
• jaundice
• generalized malaise
• sudden and severe headache

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headache
• drowsiness
• abdominal pain
• nausea
• weakness

This medication should be stored in a tightly closed container that blocks light, at a temperature between 1 degree and 30 degrees Celsius. Storing it this way can help maintain its effectiveness and prevent degradation.

Appearance

White octagonal tablet

Package unit

30 tablets/bottle, 300 tablets/bottle