New Ezytime Tablets (Ezetimibe)

Adult dosage

The recommended dose of this medication is 10 mg once a day, administered regardless of meals. When co-administered with HMG-CoA reductase inhibitors, treatment should be started at the recommended initial dose of the HMG-CoA reductase inhibitor alongside this medication, and if a high dose of HMG-CoA reductase inhibitor is already being administered, this medication should be combined while maintaining the dose of the HMG-CoA reductase inhibitor.

This medication should not be used in patients who are hypersensitive to any of its components. It is advisable not to use this medication together with certain types of drugs in patients with active liver disease or in those with a persistently elevated serum aminotransferase level without explanation. For women who are pregnant or breastfeeding, the combined use of this medication with certain lipid-lowering agents is prohibited, and caution is necessary for women of childbearing potential. Patients with severe liver dysfunction, biliary disease, or severe renal impairment should avoid concurrent use with certain lipid-lowering agents. Patients with moderate to severe liver dysfunction should be cautious in using this medication, as increased exposure may cause unexpected side effects. This medication generally has good tolerability; however, side effects such as headache, abdominal pain, diarrhea, fatigue, and myalgia may occur, so any unusual symptoms should be discussed with a physician. When this medication is used concurrently with certain lipid-lowering agents, liver enzyme levels may increase, so routine regular liver function tests are necessary. If muscle-related symptoms such as myalgia or weakness occur, notify medical personnel immediately, and in severe cases, discontinuation of the medication may be considered. Patients with impaired kidney function can also use this medication; however, caution is necessary in cases of severe renal impairment, but dose adjustment is not required. This medication may interact with other drugs, so it is essential to inform healthcare providers about any other medications being taken. Due to insufficient safety data for this medication during pregnancy or breastfeeding, consultations should be made with a doctor if pregnancy is planned or if pregnant. Use in children under 6 years is not recommended, and children and adolescents aged 6 and older should use it under a physician's direction. Elderly patients may also use this medication, but some may be more sensitive to the drug, so their condition should be monitored closely. In cases of overdose, immediate consultation with healthcare personnel is necessary, and appropriate treatment should be provided if needed. This medication should be stored out of reach of children, and it is safer not to transfer it to another container.

Serious side effects

Hives, angioedema, anaphylaxis, hepatitis, pancreatitis, thrombocytopenia, liver dysfunction, renal failure, cholecystitis, cholelithiasis, persistent elevation of liver aminotransferase levels (over three times the normal upper limit), myopathy, rhabdomyolysis, systemic edema, edema, hypertension, renal failure

Mild side effects

• Fatigue
• abdominal pain
• diarrhea
• viral infection
• pharyngitis
• sinusitis
• arthralgia
• low back pain
• cough
• dizziness

This medication is sensitive to air and moisture, so it must be stored in a tightly closed container. It is recommended to store it at room temperature, between 1 to 30 degrees Celsius. This helps maintain the effectiveness of the medication for a long time.

Appearance

White to almost white oblong tablet

Package unit

30 tablets (10 tablets/PTP x 3)