Epiduo Forte Gel 0.3%/2.5% (Adapalene/ Benzoyl Peroxide)

Adult dosage

After washing the affected area, apply a thin layer to the acne-affected area once daily in the evening. When applying, use the fingertips to avoid the eyes, lips, and mucous membranes. If skin irritation occurs, use a non-irritating moisturizer, reduce the frequency of application (e.g., every other day), or temporarily or permanently discontinue treatment. The treatment duration is determined based on a physician's diagnosis, typically showing initial clinical improvement within 1 to 4 weeks from the start of treatment.

This medication is intended for topical use on the skin, and care should be taken to avoid excessive exposure to sunlight or ultraviolet rays. Particularly, individuals sensitive to sunlight or those who are frequently exposed to sunlight should exercise extra caution when using this medication. If exposure to sunlight is unavoidable, it is advisable to apply sunscreen and wear protective clothing such as hats. Care should also be taken on windy or cold days, as skin irritation may occur. If the skin is damaged from sunburn, it is best to avoid using this medication until fully healed. It should not be used on areas with known allergies to its ingredients, open wounds, eczema, or seborrheic dermatitis. It is advisable for pregnant women or women who may become pregnant to avoid using this medication. Individuals with allergies or hypersensitivity to propylene glycol should use this medication with caution. Initial use may result in skin redness, dryness, stinging, or itching, but these symptoms generally improve over time. If skin irritation is severe or an allergic reaction is suspected, use should be discontinued immediately and a doctor consulted. Care should be taken to avoid contact with mucosal areas such as the eyes, nose, and mouth; if contact occurs, rinse thoroughly with clean water. This medication may cause discoloration if it comes into contact with hair or dyed clothing, so caution is advised. It is advisable to avoid using this medication together with other retinoids or irritative acne treatments. This medication should not be used during pregnancy; if pregnancy is confirmed, use should be discontinued immediately. Nursing mothers should avoid applying this medication to the breast area and should use it with caution. The safety for children under 12 years and elderly individuals over 65 is not established, so consultation with a physician is necessary prior to use. In case of overdose, it is important to visit a medical facility immediately for appropriate treatment. This medication should be kept out of reach of children and should not be transferred to other containers.

Serious side effects

• Angioedema
• anaphylactic reaction
• throat tightness
• difficulty breathing
• facial edema
• blisters
• hives

Mild side effects

Eyelid erythema, eyelid edema, sensory disturbances (tingling at the application site), irritant contact dermatitis, burning sensation, skin irritation, erythema, skin peeling, eczema, atopic dermatitis, itching, sunburn, rash, skin dryness, skin pain (stinging pain), allergic contact dermatitis, skin hypopigmentation, skin hyperpigmentation, burns at the application site

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. Additionally, it should be kept at room temperature between 1°C and 25°C, avoiding excessively hot or cold places.

Appearance

An opaque gel that is white or pale yellow.

Package unit

Pump type: 15g, 30g