Medication info
Dutched Tablet (R-Tocopheryl Acetate)

Dutched Tablet (R-Tocopheryl Acetate)

Prescription medicationTabletOral
Ingredient · strength
R-Thioctic Acid Tromethamine›480mg / 1 tablet
Manufacturer / importer
Sami Pharm Co., Ltd.
Appearance
Pale green rectangular film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 201800947 · Approved 2018.02.26 · Insurance code 644003960

Summary

Main use
Relief of diabetic polyneuropathy
Who takes it
Adults
Adult dose
Take 480 mg of thioctic acid tromethamine salt once daily with plenty of water, about 30 minutes before breakfast.

Ingredients

Manufacturer
Sami Pharm Co., Ltd.

Efficacy & effects

Relief of diabetic polyneuropathy

  • Diabetic polyneuropathy
View approved original text

This medication helps relieve nerve damage and pain caused by diabetic polyneuropathy. It is used to improve nerve function and reduce uncomfortable symptoms, thereby enhancing the quality of life for patients.

How to take

Adult dose

Take 480 mg of thioctic acid tromethamine salt once daily with plenty of water, about 30 minutes before breakfast.

Precautions

This medication should not be used by individuals with allergies to R-Tocopheryl Acetate, Thioctic Acid, or any other ingredients included in the medication. When taking this medication, symptoms such as sensory abnormalities, pain, headache, constipation, abdominal discomfort, dry mouth, cough, cystitis, diarrhea, and burning sensation may occur, and these symptoms are usually mild or moderate. Rarely, serious side effects such as kidney stones, lumbar canal stenosis, or facial swelling may occur, so if such symptoms arise, consult a doctor immediately. Additionally, side effects such as dry mouth, muscle pain, nausea, decreased appetite, joint pain, palpitations, and insomnia may occur during treatment with this medication. Individuals who frequently consume alcohol may have an increased risk of nerve damage, which can reduce the effectiveness of this medication, so it is advisable to avoid alcohol as much as possible. Taking this medication with supplements containing iron, magnesium, calcium, or milk could decrease its effectiveness, so it is recommended to take this medication 30 minutes before meals and to take iron or magnesium supplements during meals. Moreover, when taking this medication alongside insulin or other diabetic medications, blood sugar may drop too low, so blood glucose should be monitored frequently and medication dosage adjusted if necessary. Pregnant or nursing women should consider the benefits and risks of this medication and take it according to their doctor's instructions, and it is safest for children under 18 not to use this medication. In case of overdose, serious symptoms of intoxication including generalized convulsions and altered consciousness may occur, so if suspected, immediate medical attention should be sought. Finally, this medication should not be stored at temperatures above 30 degrees Celsius, should be kept out of the reach of children, and should not be transferred to other containers.

Side effects

  • Paresthesia
  • pain
  • sensory loss
  • headache
  • constipation
  • abdominal discomfort
  • rhinitis
  • dry mouth
  • cough
  • cystitis
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  • diarrhea
  • burning sensation
  • nephrolithiasis
  • lumbar spinal stenosis
  • facial swelling
  • dry lips
  • myalgia
  • nausea
  • decreased appetite
  • arthralgia
  • palpitations
  • insomnia
  • upper limb fractures
  • hypoglycemia
  • neurogenic bladder
  • diabetic retinopathy
  • colitis
  • benign gastric neoplasm
  • gastrointestinal bleeding
  • disease progression
  • soft tissue inflammation
  • cold
  • body pain
  • plantar fasciitis
  • herniated disc
  • thyroiditis
  • increased LDH
  • increased triglycerides
  • weight loss
  • abnormal blood sugar
  • herpes zoster
  • dysuria
  • worsening renal function
  • vaginitis
  • conjunctivitis
  • floaters
  • unspecified retinal vascular disorder
  • heart palpitations
  • acute abdominal syndrome
  • colorectal polyps
  • benign oral neoplasm
  • benign gastrointestinal neoplasm
  • gastroesophageal reflux disease
  • gastritis
  • gastroenteritis
  • dental caries
  • periodontitis
  • rectal bleeding
  • chest pain
  • peripheral edema
  • edema
  • limb pain
  • carpal tunnel syndrome
  • flank pain
  • generalized edema
  • generalized weakness
  • low back pain
  • sleep disorders
  • simple partial seizures
  • facial paralysis
  • bitter taste
  • genital pruritus
  • changes in nails
  • blisters
  • dermatitis
  • unspecified peripheral vascular disease
  • gum bleeding
  • phlegm disorders
  • bronchitis
  • throat infection
  • sinusitis
  • congestion
  • upper respiratory infection
  • allergic atopic rhinitis
  • dyspnea
  • nausea
  • vomiting
  • gastrointestinal pain
  • skin rash
  • urticaria
  • itching
  • dizziness
  • sweating
  • taste disorder
  • epigastric pain
  • dyspepsia
  • itching
  • abdominal pain
  • heartburn
  • restlessness
  • altered consciousness
  • generalized seizures
  • lactic acidosis
  • shock
  • rhabdomyolysis
  • hemolysis
  • disseminated intravascular coagulation
  • bone marrow suppression
  • multiple organ failure

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture, preferably at room temperature between 1 and 30 degrees Celsius. Storing it this way helps maintain its effectiveness.

Appearance and packaging

Appearance

Pale green rectangular film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.