Medication info

Isophen Syrup (Dexibuprofen)

OTC medicationSyrup경구
Ingredient · strength
Dexibuprofen›1.2g / 100mL
Manufacturer / importer
한국휴텍스제약(주)
Appearance
A milky white suspension syrup containing a unique fragrance in an opaque white bottle
Packaging
500 mL/bottle
Approval status
Active

MFDS item code 201800862 · Notified 2018.02.19 · Insurance code 649103831

Summary

Main use
Antipyretic effect for acute upper respiratory infection (fever)
Who takes it
Adults · Children
Adult dose
Specific dosing instructions for adults are not provided.
Child dose
For children over 6 months of age, a single dose of 0.4 to 0.6 mL/kg (5 to 7 mg/kg as dexibuprofen) may be administered every 4 to 6 hours as needed, not exceeding 4 times in one day (28 mg/kg)

Ingredients

Manufacturer
한국휴텍스제약(주)

Efficacy & effects

Antipyretic effect for acute upper respiratory infection (fever)

  • Acute upper respiratory infection
  • fever
View approved original text

This medication is used to relieve fever caused by acute upper respiratory infections. It alleviates discomfort due to fever and helps the patient recover more comfortably.

How to take

Adult dose

Specific dosing instructions for adults are not provided.

Child dose

For children over 6 months of age, a single dose of 0.4 to 0.6 mL/kg (5 to 7 mg/kg as dexibuprofen) may be administered every 4 to 6 hours as needed, not exceeding 4 times in one day (28 mg/kg)

Precautions

This medication should be consulted with a doctor or pharmacist before use by individuals who regularly consume more than 3 glasses of alcohol daily. This medication can cause gastrointestinal bleeding. It may also increase the risk of cardiovascular disease, so patients with heart diseases or risk factors should be extra cautious. If cardiovascular symptoms appear, medical consultation should be sought immediately. There is also a risk of gastrointestinal adverse reactions, so caution is especially necessary for patients with a history of gastrointestinal bleeding or ulcers, and the elderly are at greater risk. The artificial sweetener aspartame contained in this medication should not be given to patients with specific genetic disorders, such as phenylketonuria. Patients with peptic ulcers, severe blood disorders, liver failure, kidney failure, heart failure, hypertension, or history of asthma should not take this medication. Patients with hypersensitivity or allergic reactions to aspirin or other non-steroidal anti-inflammatory drugs should avoid this medication. Patients with a history of peptic ulcers or bleeding tendencies, those with poor liver or kidney function, and the elderly should use this medication with caution. Regular checks such as blood tests may be necessary while taking this medication, and if unusual symptoms occur, it should be stopped immediately and consulted with a doctor. This medication should be avoided in pregnant women, especially in late pregnancy, as it may affect the fetus, and caution is needed for breastfeeding women as well. Children and the elderly are more susceptible to adverse reactions, so it should be administered with the minimum dose carefully. This medication can interact with other non-steroidal anti-inflammatory drugs or certain medications, so inform your doctor or pharmacist if you are taking other medications. In the event of overdose, visit a medical institution immediately for gastric lavage or appropriate treatment. Lastly, this medication should be stored out of the reach of children, and care should be taken not to transfer it to other containers.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), difficulty breathing (including asthma attacks), anaphylactic shock (severe allergic reaction), severe rashes with high fever, blisters, skin peeling, pain in mouth/eye mucous membranes (Stevens-Johnson syndrome, Lyell syndrome, DRESS syndrome, acute generalized exanthematous pustulosis), yellowing of the skin or eyes (jaundice), extreme lethargy, severe swelling and shortness of breath, acute renal failure, sudden and

Mild side effects

  • Nausea
  • vomiting
  • abdominal pain
  • indigestion
  • diarrhea
  • gastric discomfort
  • thirst
  • stomatitis
  • abdominal bloating
  • constipation
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  • itching
  • rash
  • eczema
  • purpura
  • low blood pressure
  • high blood pressure
  • palpitations
  • numbness
  • tinnitus
  • dysgeusia
  • fatigue
  • fever
  • nosebleed
  • fussiness
  • facial swelling
  • indigestion
  • diarrhea

Not everyone experiences these, and they can vary from person to person.

Interactions

Drug interactions

This medication should not be used with other non-steroidal anti-inflammatory drugs, aspirin, or high doses of methotrexate. Consult with a doctor or pharmacist when using it in combination with glucocorticoids, digoxin, phenytoin, probenecid, sulfinpyrazone, sulfonylureas, diuretics, or antihypertensive agents, ACE inhibitors, furosemide, lithium, low-dose methotrexate, or coumarin anticoagulants.

Food interactions

This medication should be used with caution when consumed with alcohol.

Storage

This medication is sensitive to light and should be stored in a container that prevents light exposure. Additionally, it is important to store it at room temperature, between 15 to 25 degrees Celsius, to maintain its effectiveness.

Appearance and packaging

Appearance

A milky white suspension syrup containing a unique fragrance in an opaque white bottle

Package unit

500 mL/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

No questions yet.

For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.