Megapro Suspension (Megestrol Acetate)

Adult dosage

Shake well and take 800 mg (20 mL) of megestrol acetate once daily. In clinical trials, clinical effects were observed with daily doses of 400～800 mg (10∼20 mL) of this medicine.

This medication can pose serious risks to the fetus if used in pregnant women. Prolonged use may lead to the development of diabetes or exacerbation of pre-existing diabetes, as well as lead to hormonal abnormalities known as Cushing's syndrome. Long-term use or sudden discontinuation of this medication may result in adrenal insufficiency, which can manifest as symptoms such as hypotension, nausea, vomiting, dizziness, and weakness, necessitating caution. If adrenal insufficiency is suspected, urgent treatment along with a blood test may be required. This medication contains aspartame, an artificial sweetener that breaks down into phenylalanine, thus it should not be taken by patients with the genetic disorder phenylketonuria. Individuals who have previously experienced an allergic reaction to this medication or are pregnant or may become pregnant should avoid using it. Patients with a history of thromboembolism or those with diabetes should use this medication cautiously, as diabetes symptoms may worsen. Potential side effects include diarrhea, rash, abdominal distension, hypertension, weakness, insomnia, nausea, anemia, fever, decreased libido, dyspepsia, headache, vomiting, pneumonia. Rarely, symptoms such as visual impairment, constipation, dry mouth, heart issues, difficulty breathing, leukopenia, urinary tract infections, neurological abnormalities, hair loss, skin rashes, swelling, chest pain, and infections have also been reported. During treatment, it is essential to accurately identify and manage the causes of weight loss, as prolonged use may increase the risk of respiratory infections. Pregnant or potentially pregnant women must ensure contraception, and breastfeeding should be discontinued, as this medication can also be transmitted through breast milk and may harm the infant. Safety and efficacy in pediatric cases have not been adequately established; therefore, it is advised not to use in children. No specific severe reactions have been reported in cases of overdose; however, dialysis treatment may not be effective. This medication should be stored out of the reach of children, and care should be taken to avoid transferring it to other containers that could result in accidents or degradation of quality.

Diarrhea

This medication must be stored in special containers to avoid exposure to light and air. The appropriate storage temperature is between 15 to 25 degrees Celsius in a cool place.

Appearance

A white to cream-colored suspension with an orange flavor and scent contained in an opaque container, disperses easily when stirred.

Package unit

14 packets (10 mL/packet x 14), 7 packets (20 mL/packet x 7)